Central Fatigue

Mental fatigue that develops during prolonged exercise and is attributed to impaired function of the central nervous system; central fatigue may correlate with a buildup of tryptophan, causing sleepiness and mental fatigue
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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Peripheral fatigue is due to changes occurring distal to the neuromuscular junction, while central fatigue has its origin proximal to the neuromuscular junction representing activities within the central nervous system (Gandevia, 1998).
Thus, optional activation normally lessens throughout maximum optional isomeric functions that are a central fatigue evolve and motor unit firing percentages decreases.
Central fatigue is defined as a failure of the central nervous system to adequately drive the muscles.
Central fatigue may arise from a dopamine imbalance within the central nervous system, and we know that vitamin D has dopaminergic effects.
The "central fatigue hypothesis" was proposed with 5-HT as the modulator of fatigue (26), because increased CNS concentrations of this neurotransmitter during exercise would promote increased lethargy and higher perceived exertion, likely by modifying the tolerance to pain or discomfort, which would limit mental and physical performances (9).
Central nervous system- (CNS-) related factors (central fatigue) and peripheral factors (peripheral fatigue) may both contribute to weakness and fatigue [13].
Fatigue in medical term can be classified into chronic fatigue syndrome (CFS), central fatigue, and peripheral fatigue.
Gandevia, "The effect of a contralateral contraction on maximal voluntary activation and central fatigue in elbow flexor muscles," Experimental Brain Research, vol.
The level 15 of the Borg Scale is correlated with at least 75% of V[O.sub.2] max and used to quantify the amount of fatigue in central fatigue protocols (25).
This is a significant topic of discussion in the dance medicine community, (27,28) and both peripheral and central fatigue have been implicated in dance related injury.
The post-match transient reductions in NMF may be the result of central fatigue, resulting in a reduction in voluntary muscle activation.
Central fatigue refers to superior processes and can be defined as a failure on the voluntary muscle activation that is progressively induced by the progression of exercise (Williamson, 2010).

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