Central Fatigue

Mental fatigue that develops during prolonged exercise and is attributed to impaired function of the central nervous system; central fatigue may correlate with a buildup of tryptophan, causing sleepiness and mental fatigue
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Central fatigue may arise from a dopamine imbalance within the central nervous system, and we know that vitamin D has dopaminergic effects.
Pharmacological manipulations of the activity of 5-HT in the CNS induced changes in physical performance, which supports the theory of participation of this neurotransmitter in the central fatigue mechanisms.
2] max and used to quantify the amount of fatigue in central fatigue protocols (25).
The ability of branchedchain amino acids (BCAA) to compete with tryptophan for crossing the blood brain barrier through the same transporter has provoked the hypothesis that the supplementation of these amino acids could reduce cerebral serotonin synthesis and prevent central fatigue during prolonged exercise (Blomstrand et al.
This is a significant topic of discussion in the dance medicine community, (27,28) and both peripheral and central fatigue have been implicated in dance related injury.
The post-match transient reductions in NMF may be the result of central fatigue, resulting in a reduction in voluntary muscle activation.
Central fatigue refers to superior processes and can be defined as a failure on the voluntary muscle activation that is progressively induced by the progression of exercise (Williamson, 2010).
sup][1] Physical fatigue is the bodily experience of exhaustion following strenuous physical effort and mental or central fatigue is the subjective self-reported feeling of fatigue.
Friedman (2009) describes central fatigue as the "failure of physical and mental tasks that require self-motivation and internal cues in the absence of demonstrable cognitive failure or motor weakness" (p.
These psychological factors are included in the concept of central fatigue (e.
Consequently, as brain function is dependent upon the interaction of a number of systems, it is unlikely that a single neurotransmitter is responsible for central fatigue (165).

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