central dogma of molecular biology

(redirected from Central Dogma Of Genetics)

central dogma of molecular biology

The outdated principle which states that proteins are made from RNA, which in turn is made from DNA. Other permutations are found in nature; e.g., RNA viruses use a reverse transcriptase to make complementary DNA.
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Genetics, inheritance and evolution are more complicated than the one-way street of DNA to RNA to protein that is still described (and taught) as the central dogma of genetics (see Figure 1, p20).
Genetic loophole The occasional switch of a chemical unit in RNA to a slightly different form can cause a cell's protein-building machinery to roll right through a molecular stop sign, a find that violates the central dogma of genetics (SN: 7/16/11, p.
The "central dogma of genetics," a phrase coined by Crick, argues that information in a cell flows from DNA to RNA to protein.

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