According to some studies Centor criteria
are the most reliable predictive clinical factors for diagnosis of pharyngitis caused by GABHS.
Most cases are diagnosed clinically, and the Centor criteria
are based on clinical evaluation of symptoms and signs.
Upon exam, the patient had 3 Centor Criteria, * and a 10-day course of amoxicillin therapy was initiated.
Centor Criteria for Strep Pharyngitis: 1 point for each of the following criteria: 1) history of fever, 2) tonsillar exudates, 3) anterior cervical adenopathy, 4) absence of cough.
Because we wished to concentrate on viral pharyngitis, we used the Centor criteria
to exclude patients with GABHS pharyngitis.
Standardized clinical decision rules, such as the Centor criteria, can identify patients with low likelihood of group A beta-hemolytic streptococcal (GABHS) pharyngitis who require no further evaluation or antibiotics (strength of recommendation [SOR]: A, based on validated cohort studies).
The 4 Centor criteria (history of fever, anterior cervical adenopathy, tonsillar exudates, absence of cough) are well validated in adult populations (Table 1), while other clinical prediction rules (such as McIssac) are validated in populations with children and adults (Table 2).
The first option is empiric treatment for patients with three or four Centor criteria
and no treatment for all others.
7) The Centor criteria
were developed to estimate the probability of acute GABHS pharyngitis in newly presenting patients.