cell cycle

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cycle

 [si´k'l]
a succession or recurring series of events.
cardiac cycle a complete cardiac movement, or heart beat, including systole, diastole, and the intervening pause.
Cardiac cycle. From Applegate, 2000.
cell cycle the cycle of biochemical and morphological events occurring in a reproducing cell population; it consists of the S phase, occurring toward the end of interphase, in which DNA is synthesized; the G2 phase, a relatively quiescent period; the M phase, consisting of the four phases of mitosis; and the G1 phase of interphase, which lasts until the S phase of the next cycle.
citric acid cycle tricarboxylic acid cycle.
estrous cycle the recurring periods of estrus in adult females of most mammalian species and the correlated changes in the reproductive tract from one period to another.
hair cycle the successive phases of the production and then loss of hair, consisting of anagen, catagen, and telogen.
menstrual cycle see menstrual cycle.
ovarian cycle the sequence of physiologic changes in the ovary involved in ovulation; see also ovulation and reproduction.
reproductive cycle the cycle of physiologic changes in the reproductive organs, from the time of fertilization of the ovum through gestation and childbirth; see also reproduction.
sex cycle (sexual cycle)
1. the physiologic changes that recur regularly in the reproductive organs of nonpregnant female mammals.
2. the period of sexual reproduction in an organism that also reproduces asexually.
tricarboxylic acid cycle the cyclic metabolic mechanism by which the complete oxidation of the acetyl portion of acetyl-coenzyme A is effected; the process is the chief source of mammalian energy, during which carbon chains of sugars, fatty acids, and amino acids are metabolized to yield carbon dioxide, water, and high-energy phosphate bonds. Called also citric acid cycle, Krebs cycle, and TCA cycle.
 Central pathways of metabolism: How the body produces energy from the energy-containing nutrients using the tricarboxylic acid cycle. From Davis and Sherer, 1994.
urea cycle a cyclic series of reactions that produce urea; it is a major route for removal of the ammonia produced in the metabolism of amino acids in the liver and kidney.

cell cy·cle

the periodic biochemical and structural events occurring during proliferation of cells such as in tissue culture; the cycle is divided into phases called G0, Gap1 (G1), synthesis (S1), Gap2 (G2), and mitosis (M). The period runs from one division to the next.
Synonym(s): mitotic cycle

cell cycle

n.
The series of events involving the growth, replication, and division of a eukaryotic cell.

cell cy·cle

(sel sī'kĕl)
The periodic biochemical and structural events occurring during proliferation of cells, such as in tissue culture.
Cell cycleclick for a larger image
Fig. 96 Cell cycle . The interphase stages.

cell cycle

the series of stages through which a cell progresses when it is actively dividing. In EUKARYOTES, the cycle consists of three subdivisions of INTERPHASE (G1, S and G2) plus MITOSIS.

cell cy·cle

(sel sī'kĕl)
The periodic biochemical and structural events occurring during proliferation of cells, such as in tissue culture.
References in periodicals archive ?
The synchronization was also found to be remarkably robust against temperature changes, which is known to affect the cell-cycle clock, changing the rhythm of cell divisions.
Thus, we performed a series of in vitro experiments to determine whether ROS levels, apoptosis, and cell-cycle progression can be altered in ECs by manipulating Bach1 expression.
Antiproliferative effects of C47 derivatives are mediated at least in part by arrest of cell-cycle progression at GrS.
A simple model is that the total time required for the downstream gene of Brachyury to restrict cell division corresponds to the time for the three rounds of cell-cycle progression.
On the other hand, normal proliferating cells overcame the imposed G2/M cell-cycle arrest within 12 hours, survived and continued to proliferate.
A progressive decrease in Rb2/ p130 expression from hyperplastic endometrium through atypical hyperplasia to poorly differentiated carcinomas suggest the involvement of this negative cell-cycle regulator in endometrial carcinogenesis.
MKC-1 is an oral cell-cycle regulator with activity against the mTOR pathway.
Categories in which the proportion of IR-responsive genes exceeded expectation based on chance included cell cycle, cell proliferation, DNA and RNA metabolism, M phase of mitotic cell cycle, S phase of mitotic cell cycle, response to DNA damage stimulus, DNA repair, and cell-cycle checkpoint (Table 2).
Although p53 is a key cell-cycle regulator, reduced p53 activity didn't pose a danger in bladder cancer patients who had normal p21 levels.