cell-penetrating peptide


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cell-penetrating peptide

A peptide that readily crosses cell membranes and therefore can influence cellular functions or carry other molecules that can directly or indirectly perform the same tasks.
See also: peptide
References in periodicals archive ?
First-generation approaches to intracellular biologics, such as cell-penetrating peptides, have not realized their full potential due to limited uptake of larger macromolecules into cells and limited tolerability.
Academic partners have unique knowledge and technologies on supercharged viral proteins-derived cell-penetrating peptides (eg from Dengue virus) and ultra-resistant cyclic peptides that may be transferred to the industrial partners, which in turn have specialized proprietary technologies on anticancer and/or peptide drugs technologies.
Cell-penetrating peptides are often investigated as drug delivery vectors and are able to cross the cell membrane, although the exact mechanism for this is unknown.