Langel, "Assessing the uptake kinetics and internalization mechanisms of cell-penetrating peptides
using a quenched fluorescence assay," Biochimica et Biophysica Acta, vol.
Neundorf, "Dimerization of a cell-penetrating peptide
leads to enhanced cellular uptake and drug delivery," Beilstein Journal of Organic Chemistry, vol.
Good, "Cell entry and antimicrobial properties of eukaryotic cell-penetrating peptides
," TheFASEB Journal, vol.
for the delivery of nucleic acids.
Aguilera et al., "Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides
decreases residual cancer and improves survival," Proceedings of the National Academy of Sciences of the United States of America, vol.
CNTs can carry significant amounts of medicinal materials within their structures and then translocate through plasma membranes in a manner resembling cell-penetrating peptides
. Over the past few years, several research groups have demonstrated the ability of both single-walled CNTs (SWCNTs) and multi-walled CNTs to move inside a variety of cell types and deliver both therapeutic and diagnostic small molecules to the cells.
Wang's team attached cell-penetrating peptides
to molecules from cells of a skin cancer known as melanoma.
Academic partners have unique knowledge and technologies on supercharged viral proteins-derived cell-penetrating peptides
(eg from Dengue virus) and ultra-resistant cyclic peptides that may be transferred to the industrial partners, which in turn have specialized proprietary technologies on anticancer and/or peptide drugs technologies.
Wong, "Argininerich cell-penetrating peptides
," FEBS Letters, vol.584, no.9, pp.