genome

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Related to Cell genome: genomic DNA

genome

 [je´nōm]
the complete set of genes, hereditary factors contained in the haploid set of chromosomes; the human genome has an estimated 30,000 to 40,000 genes. adj., adj genom´ic.

ge·nome

(je'nōm, -nom),
1. A complete set of chromosomes derived from one parent, the haploid number of a gamete.
See also: Human Genome Project.
2. The total gene complement of a set of chromosomes found in higher life forms (the haploid set in a eukaryotic cell), or the functionally similar but simpler linear arrangements found in bacteria and viruses.
See also: Human Genome Project.
[gene + -ome, suffix denoting a defined system or microcosm, fr. G. -ōma, noun suffix]

genome

/ge·nome/ (je´nōm) the complete set of hereditary factors contained in the haploid set of chromosomes.genom´ic

genome

(jē′nōm′)
n.
1. The total genetic content contained in a haploid set of chromosomes in eukaryotes, in a single chromosome in bacteria or archaea, or in the DNA or RNA of viruses.
2. An organism's genetic material.

ge·no′mic (-nō′mĭk) adj.

genome

[jē′nōm]
Etymology: Gk, genein, to produce
the complete set of genes in the chromosomes of each cell of a specific organism. genomic, adj.

genome

Genetic structure Genetics All the genetic information in an organism's chromosomes and mitochondria; its size is given in base pairs. See Base pair, Chromosome, Mitochondrial genome, Nuclear genome.

ge·nome

(jē'nōm)
1. A complete set of chromosomes derived from one parent, the haploid number of a gamete.
2. The total gene complement of a set of chromosomes found in higher life forms (the haploid set in a eukaryotic cell), or the functionally similar but simpler linear arrangements found in bacteria and viruses.
See also: Human Genome Project
[G. genos, birth + (chromos) ome]

genome

The complete set of CHROMOSOMES, together with the MITOCHONDRIAL DNA, containing the entire genetic material of the cell.

genome

the complete complement of genetic material in a cell, or carried by an individual.

Genome

The genetic makeup of a cell, composed of DNA.
Mentioned in: Malignant Melanoma

genome

total gene complement of a set of chromosomes

genome

The complete set of genes in an individual. In humans it is estimated at approximately 30 000 genes and over three billion base pairs (two nucleotides joined together across a double helix) of DNA.

ge·nome

(jē'nōm)
Complete set of chromosomes derived from one parent; haploid number of a gamete.

genome (jē´nōm),

n the total gene complement of a set of chromosomes found in higher life forms.
genome, human,
n the complete set of genes in the chromosomes of each cell.

genome

all of the genes carried by a gamete, i.e. the complete set of hereditary factors contained in the chromosomal DNA. For some viruses, the genome is RNA.

diploid genome
having two genetically identical RNA molecules of RNA, characteristic of retroviruses.
integrated genome
the integration of the viral DNA into the cellular DNA of the host, as occurs in some kinds of persistent infections and the induction of tumors.
segmented genome
the genome is composed of separate segments. A characteristic of some viruses.
References in periodicals archive ?
Zhang's team analyzed Tet1's occupancy across the entire mouse embryonic stem cell genome.
Many mechanisms for integration of transfected plasmids into mammalian cell genomes such as CHO cells have been suggested in publications, but none of the proposed mechanisms explains the results that are obtained when analyzing the genomes and transgene structures of CHO production cell lines.
This edition has been revised and updated to include recent advances and information on the tumor microenvironment, metastatic dissemination, tumor immunology, cancer stem cells, the epithelial-mesenchymal transition, multi-step tumorigenesis, invasion and metastasis, mutation of cancer cell genomes, epigenetic contributions, microRNA involvement, and the Warburg effect, with more on traditional therapy and a new list of key techniques.
In one, bacteria and viruses--which are naturally able to penetrate cells--are deployed as delivery vehicles to shuttle genes directly into plant cell genomes.
These observations have been made possible thanks to mass sequencing of tumor cell genomes.
But in practice, editing T cell genomes with CRISPR/Cas9 has proved surprisingly difficult, said Alexander Marson, PhD, a UCSF Sandler Fellow, and senior and co-corresponding author of the new study.
Recently, the advent of next-generation sequencing technologies has provided new strategies for the systematic genome-wide identification of somatic changes in cancer cell genomes.
Here we propose to study a thousand single cell genomes from different regions in primary tumors and matched metastases.