cephalothin

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cephalothin

 [sef´ah-lo-thin]
a semisynthetic first-generation cephalosporinantibiotic, effective against a wide range of gram-positive and a limited range of gram-negative bacteria.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

cephalothin

Cefalotin® Infectious disease A parenteral semisynthetic derivative of cephalosporin C, and 3rd generation broad-spectrum cephalosporin
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Furthermore, due to the inappropriate prescription, it was not surprising that our study found that resistance to penicillin, cefalotin, cefazoline, ceftriaxone, azithromycin and tetracycline were 100%, 100%, 100%, 100%, 62.12% and 57.57%, respectively.
Our data revealed that tetK, tetM, ermA, ermC, aacA-D, linA, msrA, vatA, vatC and vatB genes and resistance to penicillin, cefalotin, cefazoline, ceftriaxone, azithromycin and tetracycline were the most commonly detected characteristics of the MRSA strains isolated from hospitals infections.
However, cefazolin resistance increased from 32.2% to 41.6%, cefalotin resistance increased from 53.5% to 65% and cefaperazon resistance increased from 25.5% to 31.1%.
The maximum and minimum of antibiotic resistance against gram negative bacteria were 93.3% for Cefalotin and 50% for Amikacin.
Amikacin 148 48.0 Ampicillin 133 2.3 Ceftriaxone 129 33.3 Cefalotin 153 11.8 Chloramphenicol 82 52.4 Trimethoprim/ 178 57.3 sulfamethoxazole Gentamicin 206 44.2 Imipenem 76 97.3 Cefepime 141 73.0 Ceftazidime 121 67.8 Escherichia coli Amikacin 71 53.0 Ampicillin 63 12.7 Ceftriaxone 64 50.0 Cefalotin 87 33.3 Chloramphenicol 43 79.1 Trimethoprim/ 100 27.0 sulfamethoxazole Gentamicin 108 61.1 Imipenem 33 97.0 Tobramycin 66.7 36.0 Piperacillin-Tazobactam 91 70.3 Pseudomonas Amikacin 617 39.4 aeruginosa Ceftazidime 558 16.3 Ceftriaxone 547 7.9 Chloramphenicol 456 30.2 Ciprofloxacin 481 94.6 Gentamycin 904 41.6 Kanamycin 473 4.6 Imipenem 91 68.1 Tobramycin 329 30.7 Enterobacter spp.
Minimum inhibitory concentrations (disk diffusion method) were 2 mg/L for amoxicillin, 2 mg/L for cefalotin, 0.09 mg/L for doxycycline, 0.03 mg/L for gentamicin, [is less than] 4 mg/L for vancomycin, 16 mg/L for erythromycin, and 20 mg/L for trimethoprim-sulfamethoxazole.
The most prevalent phenotypes were resistant to levofloxacin (51.8%), amoxicillin/clavulanic acid (70.4%), ampicillin (81.5%), cefalotin (88.8%), tetracycline (100%) and streptomycin (100%).
dysenteriae type 1 was resistant to amoxicillin, amoxicillin in combination with clavulanic acid, tetracycline, chloramphenicol, cefsulodin, and cotrimoxazole; it was sensitive to nalidixic acid, piperacillin, cefalotin, ceftazidin, gentamicin, and ofloxacin.
Amikacin 83% Amox/clavul 0% Ampicillin 0% Aztreonam 21% Cefalotin 0% Cefepime 97% Cefotaxime 79% Cefoxitin 0% Ceftazidime 80% Ceftriaxone 67% Cefuroxime 0% Ciprofloxacin 87% Ertapenem 97% Gentamicin 87% Imipenem 100% Levofloxacin 100% Meropenem 100% Pipe-tazo 80% Co-trimoxazole 87% Note: Table made from bar graph.
These isolates comparing the results of susceptibility by year showed increase of rates of resistance to kanamycin, cefalotin, ampicillin, gentamycin, amikacin, ceftriaxone, ceftazidime, tobramycin (p-value < 0.05).
(a) Statistically significant; (b) Cefipime and Ceftazidime; (c) Ciprofloxacin and Levofloxacin; (d) Ceftriaxone, Cefuroxime, Cefazolin and Cefalotin; (e) Ampicillin, Ampicillin- Sulbactam, Amoxicillin, Amoxicillin-Clavulanate, Oxacillin.