(redirected from Caveolin 2)


The 22-kD transmembrane protein associated with the membranes of caveolae and with Golgi membranes; believed to function in signal transduction, in cholesterol transport, and metabolism of the cell.
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Caveolin 1 and Caveolin 2 are associated with breast cancer basal-like and triple-negative immunophenotype.
6 Lu et al, (53) 2008 Caveolin 1 36 Rakha et al, (43) 2009 Caveolin 2 20 Rakha et al, (43) 2009 P-cadherin 79 Rakha et al, (43) 2009 p16INK4a 89 Bohn et al, (30) 2010 Abbreviations: CK, cytokeratin; EGFR, epidermal growth factor receptor; IHC, immunohistochemistry; IMP3, insulin- like growth factor II mRNA-binding protein 3; VEGF, vascular endothelial growth factor.
Distribution and significance of caveolin 2 expression in normal breast and invasive breast cancer: an immunofluorescence and immunohistochemical analysis.