ribozyme(redirected from Catalytic RNA)
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A nonprotein RNA biocatalyst; several cleave precursors of tRNA to yield functional tRNAs; others act on rRNA; plays a key role in intron splicing events.
[ribonucleic acid + -zyme]
Farlex Partner Medical Dictionary © Farlex 2012
An RNA molecule that acts as a catalyst, especially for the cleavage of RNA strands at specific sites.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.
ribozymeOne of a unique class of RNA molecules that can act as cleaving enzymes in addition to storing genetic information. This is a notable exception to the general rule that all enzymes are proteins. Ribozymes form complementary base pairs in the normal manner but can cleave segments of nascent RNA during the splicing process of the formation of mature RNA transcripts of DNA. Ribozymes can be used in various ways as treatment modalities.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
ribozymean RNA molecule with catalytic activity. Ribozymes include (a) molecules involved in processing RNA precursor molecules by cleaving PHOSPHODIESTER BONDS, for example in self-SPLICING of some precursor rRNA INTRONS; and (b) molecules catalysing key cellular reactions, for example rRNA of the large ribosomal subunit (see RIBOSOME), which is closely involved with the peptidyl transferase activity that catalyses PEPTIDE BOND formation in TRANSLATION. Ribozymes are found in EUCARYOTES, PROKARYOTES, VIRUSES and VIROIDS.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005