carnosine


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carnosine

 [kahr´no-sēn]
a dipeptide composed of beta-alanine and histidine, found in skeletal muscle of vertebrates.

car·no·sine

(kar'nō-sēn),
N-β-alanyl-l-histidine; the dominant nonprotein nitrogenous component of brain tissue, first found in relatively high amounts in muscle; chelates copper and activates myosin ATPase.
Synonym(s): ignotine, inhibitine
[L. carnosus, fleshy, fr. caro, flesh, + -ia]

carnosine

/car·no·sine/ (-sēn) a dipeptide composed of β-alanine and histidine, found in skeletal muscle and the brain in humans; it may be a neurotransmitter.

carnosine

[kär′nōsēn]
Etymology: L, caro,
a dipeptide composed of beta-alanine and histidine, in humans found in skeletal muscle and in the brain, particularly in the primary olfactory pathways. It may play a role as a neurotransmitter.

carnosine

A dipeptide composed of beta-alanine and histidine that is concentrated in skeletal muscle and the brain. While its function is unknown, carnosine has antioxidant properties, counteracts glycation, chelates divalent metal ions and acts as a buffer, stabilising the pH of anaerobically contracting muscle.

carnosine

a dipeptide composed of beta-alanine and histidine, found in skeletal muscle of vertebrates.
References in periodicals archive ?
Calcium sensitizing action of carnosine and other endogenous imidazoles in chemically skinned striated muscle.
in 1986 on carnosine in wound healing showed that rats treated locally with carnosine exhibited greater tensile skin strength at an incision site after hydrocortisone had been administered to hinder healing.
The absorption of orally supplied b-alanine and its effect on muscle carnosine synthesis in human vastuslateralis, 30: 279-289.
Carnosine is scientifically proven to inhibit the glycation process by 33%, notes the spokeswoman.
Supplementation with [beta]-alanine vs placebo for 7 wk in 9+9 elite rowers increased the content of the intramuscular buffer carnosine in muscles and enhanced 2000-m ergometer performance by 4.
The soft lens, all-in-one solution, contains carnosine, an antioxidant that supports the natural defence mechanism of the cornea against harmful free radicals and Provitamin B5 (Dexpanthenol) which cares, supports and protects regeneration of damaged corneal cells.
Compared with carnosine (50 mg/ kg), as positive control ESF (20mg/kg) significantly reduced infarct volume and neurological deficits.
This book summarizes the knowledge on metabolic transformation of carnosine in excitable tissues of animals and human beings, and analyzes the nature of its biological activity.
A source of a range of endogenous antioxidants and other bioactive substances, including taurine, carnitine, carnosine, ubiquinone, glutathione and creatine
Effect of carnosine homocarnosine and anserine on hydroxylation of the guanine moiety in 2'-deoxyguanosine, DNA and nucleohistone with hydrogen peroxide in the presence of nickel(II).
Specifically, although under appropriate conditions both isoforms catalyze the hydrolysis of the dipeptide carnosine ([beta]-alanyl-L-histidine), only serum carnosinase is able to hydrolyze homocarnosine ([gamma]-aminobutyryl-L-histidine) (2, 9,10).