Carney triad


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Carney triad

(kar′nē)
[J. Aidan Carney, contemporary U.S. pathologist]
The combined presence of gastric stromal tumors, paragangliomas, and pulmonary chondromas in a patient.
References in periodicals archive ?
Carney et al., "SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors," Modern Pathology, vol.
(124) Interestingly, although germline mutations have been identified in association with Carney-Stratakis syndrome, mutations in SDH genes have not been found in patients with Carney triad, and the mechanism for deficient SDH function in Carney triad is uncertain at this time.
Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney triad. Am J Med Genet.
Carney triad comprises gastric GIST, paraganglioma, and pulmonary chondroma.
A subset of patients with pediatric GIST have Carney-triad, and therefore, GIST in a child should trigger evaluation for potential Carney triad.