Consistent with the previous findings (1), all SVA isolates from different countries clustered together under the genus Senecavirus, which is most closely related to the genus Cardiovirus
of the family Picornaviridae (Figure).
Circulation of 3 lineages of a novel Saffold cardiovirus in humans.
Saffold virus, a human Theiler's-like cardiovirus, is ubiquitous and causes infection early in life.
Sequence and phylogenetic analyses of Saffold cardiovirus from children with exudative tonsillitis in Yamagata, Japan.
Cultivation and serological characterization of a human Theiler's-like cardiovirus associated with diarrheal disease.
Circulation of three lineages of a novel Saffold cardiovirus in humans.
Saffold cardiovirus infection in children associated with respiratory disease and its similarity to Coxsackievirus infection.
SAFV is genetically related to Theiler viruses and is believed to constitute a novel cardiovirus species (1,7).
Fecal samples positive for Saffold cardiovirus, Beijing, People's Republic of China, March 2006-November 2007 * Sample no.
To the Editor: A new member of the genus Cardiovirus
, termed Saffold virus (SAFV), was discovered recently in stool specimens and nasopharyngeal aspirate samples from patients with fever of unknown origin, respiratory symptoms, or gastroenteritis; these have been considered the first documented reports of cardiovirus
infection in humans (1-4).
Picornaviruses are currently divided into 8 genera: Enterovirus, Aphthovirus, Cardiovirus
, Hepatovirus, Parechovirus, Erbovirus, Teschovirus, and Kobuvirus (1).
To the Editor: The picornaviruses constitute a large, diverse family of positive-sense RNA viruses, which comprise 8 genera: Enterovirus, Aphthovirus, Cardiovirus
, Hepatovirus, Parechovirus, Erbovirus, Kobuvirus, and Teschovirus (1).