(redirected from Cardiolipins)
Also found in: Dictionary, Encyclopedia.
Related to Cardiolipins: diphosphatidylglycerol

car·di·o·lip·in (CL),

A 1,3-bis(phosphatidyl)glycerol found in many biomembranes with immunologic properties; used in serologic diagnosis of syphilis. When mixed with lecithin and cholesterol cardiolipin will combine with the Wassermann antibody but not with the treponema-immobilizing antibody.
Farlex Partner Medical Dictionary © Farlex 2012


A phospholipid usually obtained from beef heart, used in combination with phosphatidylcholine and cholesterol as an antigen to diagnose syphilis.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A 1,3-bis(phosphatidyl)glycerol found in many biomembranes with immunologic properties; used in serologic diagnosis of syphilis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


A substance derived from beef heart muscle and once much used in the WASSERMAN REACTION test for SYPHILIS. Current interest is focused on immunoglobulins known as anticardiolipin antibodies.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

Patient discussion about cardiolipin

Q. what is anh cardiolipin antibody

A. Cardiolipin is a protein that is very common in the body. Mostly on heart and skeletal muscles. During several illnesses, mostly autoimmune, our body creates an antibody against it that do great damage and needs to cbe controlled.

More discussions about cardiolipin
This content is provided by iMedix and is subject to iMedix Terms. The Questions and Answers are not endorsed or recommended and are made available by patients, not doctors.
References in periodicals archive ?
Akamatsu, "A somatic cell mutant defective in phosphatidylglycerophosphate synthase, with impaired phosphatidylglycerol and cardiolipin biosynthesis," Journal of Biological Chemistry, vol.
Greenberg, "Cellular functions of cardiolipin in yeast," Biochimica et Biophysica Acta, vol.
Sparagna, "Role of cardiolipin alterations in mitochondrial dysfunction and disease," American Journal of Physiology: Cell Physiology, vol.
Poll-The et al., "The enigmatic role of tafazzin in cardiolipin metabolism," Biochimica etBiophysica Acta, vol.
Vaz, "Cardiolipin, the heart of mitochondrial metabolism," Cellular and Molecular Life Sciences, vol.
Zhu, "Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases," Free Radical Research, vol.
Sparagna, "The role of calcium-independent phospholipase A2 in cardiolipin remodeling in the spontaneously hypertensive heart failure rat heart," Journal of Lipid Research, vol.
Han, "Cardiolipin remodeling in diabetic heart," Chemistry and Physics of Lipids, vol.
Chen et al., "Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome," Molecular Microbiology, vol.
Schlame et al., "Absence of cardiolipin in the crd1 null mutant results in decreased mitochondrial membrane potential and reduced mitochondrial function," The Journal of Biological Chemistry, vol.
Gross, "Shotgun lipidomics of cardiolipin molecular species in lipid extracts of biological samples," Journal of Lipid Research, vol.
Sims et al., "Myocardial regulation of lipidomic flux by cardiolipin synthase: setting the beat for bioenergetic efficiency," The Journal of Biological Chemistry, vol.