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Chief or principal; in embryology, relating to the main venous drainage.
[L. cardinalis, principal]


A gene on chromosome 19q13.33 that encodes a protein involved in apoptosis which is highly expressed in the lung, ovary, testis and placenta. CARD8 inhibits NF-kappa-B activation and regulates cell responses controlled by NF-kappa-B transcription factor. It may be part of the inflammasome, a protein complex that activates proinflammatory caspases.
References in periodicals archive ?
Today, mountain-grown Napa grapes have been the foundation of Cardinale, especially those from Mount Veeder, Howell Mountain, Spring Mountain and Diamond Mountain.
Sua eficiencia em relacao ao ganho de forca, potencia muscular, flexibilidade e equilibrio, assim como os mecanismos fisiologicos que induziriam a esses ganhos, tornaram-se alvo de diversas investigacoes (Cardinale e Bosco, 2003; Jacobs e Burns, 2009; Torvinen e colaboradores, 2002; Cardinale e Lin, 2003; Blotner e colaboradores, 2006; De Ruiter e colaboradores, 2003; Sands e colaboradores, 2006).
Most famous internationally for the "brains and beauty" she brought to Blake Edward's all-time-hit, The Pink Panther in 1963 co-starring Peter Sellers and David Niven, Cardinale has fought her whole life.
Also during the evening the festival gave two lifetime achievement awards to a European cinema icon, Italian actress Claudia Cardinale, and to Egyptian screen legend Sawsan Badr.
El joven arquitecto tiene cuentas pendientes con su patria, adaptarse a las formas culturales, conflictos de clase, lengua y orientacion sexual; todo se complica cuando empieza una relacion con Bilal (Salim Kekiouche), el mozo de la casa, y debe enfrentar la intolerancia de su madre, Sara (Claudia Cardinale).
See also: "The biliary tree--a reservoir of multipotent stem cells;" Vincenzo Cardinale, Yunfang Wang, Guido Carpino et al.; Nature Reviews Gastroenterology and Hepatology 9,231-240(1 April 2012), DOL10.1038/nrgastro.2012.23
Nell'aprile 1574 il cardinale Tolomeo Gallio, segretario di Stato di Gregorio XIII, scrisse al Sauli che ii pontefice era allarmato poiche i ministri della citta rifiutavano di riconoscere le certificazioni della condizione clericale--indispensabili per ottenere ii rimborso--rilasciate dai vescovi: essi infatti intendevano assumersi il compito di tale verifica: innovazione, questa, <<di molto pregiuditio alla giurisditione ecclesiastica eta la dignita del cleros>>.
1 Phytopathology study, California emerged as the top suspect for the pathogen, Seiridium cardinale, that is the cause of cypress canker disease.
Luis Alberto Urrea and Christopher Cardinale. Cinco Puntos Press, 2010.
I now have the privilege of introducing the person who has been working on this event tirelessly for the last few months, and has brought everything together for us today, Jessie Cardinale, the Law Review's Executive Editor for State Constitutional Commentary.
Henry Fonda is chillingly cast against type as a coldblooded mercenary hired to force a widow (Claudia Cardinale) from her land.