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Chief or principal; in embryology, relating to the main venous drainage.
[L. cardinalis, principal]


/car·di·nal/ (kahr´dĭ-n'l)
1. of primary or preeminent importance.
2. in embryology, pertaining to the main venous drainage.


Etymology: L, cardo, hinge
pertaining to something so fundamental that other things hinge on it, such as a cardinal trait that influences one's total behavior.


A gene on chromosome 19q13.33 that encodes a protein involved in apoptosis which is highly expressed in the lung, ovary, testis and placenta. CARD8 inhibits NF-kappa-B activation and regulates cell responses controlled by NF-kappa-B transcription factor. It may be part of the inflammasome, a protein complex that activates proinflammatory caspases.
References in periodicals archive ?
Veamos como se concreta lo comentado hasta aqui en el tratamiento que reciben Claudia Cardinale, Elisabeth Taylor y Brigitte Bardot en Cine en 7 Dias.
Shot in just 25 days Cardinale says it was "like a theatre" saying she was inspired by the energy of a man just about to celebrate his 104th year on the planet.
A ogni modo, nel dicembre 1616, il nunzio Paolo Emilio Filonardi, vescovo di Amalfi, informava il cardinale nipote Scipione Borghese che la citta di Napoli intendeva far fronte ai suoi debiti con l'imposizione di un grano per rotolo di carne e di una tassa sulla farina per il pane fatto in casa.
For example Cardinale writes six paragraphs reporting Billy's marital history: "Trudi went back to work and started going out with her friends again on a regular basis.
In those days, everyone in the family called Cardinale "Mama Rosa.
Bert Grayson, officially a member of the Hall's class of '05 with Len Cardinale, was recognized as a Contributor to the Sport.
In Trenton," said Senator Gerald Cardinale, the lone advocate of the idea in the Legislature, "public policy is often decided not on merits but on who yells the loudest.
For me, that person was young Matthew Cardinale, a Point Foundation scholar and journalist who has written for Advocate.
3) The dress worn by Claudia Cardinale in ``Once Upon a Time in the West'' is part of the Autry's Leone exhibit.
We evaluated a number of solutions from banks and technology companies, considering both their hard and soft benefits," says Rite Aid senior vice president of category management Jerry Cardinale.
Cardinale E, Colbachini P, Perrier-Gros-Claude JD, Gassama A, Aidara-Kane A.
As a result, Rite Aid has made great strides in managing its inventory more efficiently, says Jerry Cardinale, the chain's senior vice president of category management.