cardiac muscle

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Related to Cardiac muscle cell: smooth muscle cell, skeletal muscle cell

car·di·ac mus·cle

the involuntary muscle comprising the myocardium and walls of the pulmonary veins and superior vena cava, consisting of anastomosing transversely striated muscle fibers formed of cells united at intercalated discs; the one or two nuclei of each cell are centrally located and the longitudinally arranged myofibrils have considerable sarcoplasm around them; connective tissue is limited to reticular and fine collagenous fibers; contraction is rhythmic and intrinsically stimulated.
Synonym(s): muscle of heart
Farlex Partner Medical Dictionary © Farlex 2012

cardiac muscle

n.
The specialized striated muscle tissue of the heart; the myocardium.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

car·di·ac mus·cle

(kahr'dē-ak mŭs'ĕl)
The muscle forming the myocardium, consisting of anastomosing transversely striated muscle fibers formed of cells united at intercalated discs.
Synonym(s): muscle of heart.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
Cardiac muscleclick for a larger image
Fig. 91 Cardiac muscle . The intercalated discs enable the rapid transmission of excitatory waves across the tissue.

cardiac muscle

a type of vertebrate muscle found only in the HEART, which appears to be halfway between INVOLUNTARY MUSCLE and STRIATED MUSCLE in that its fibres are striated, but contain a single nucleus (see Fig. 91 ). The action of cardiac fibres is to produce strong and rhythmic contractions from within, even when removed from the body (see MYOGENIC CONTRACTION). Unlike striated muscle, cardiac muscle does not become fatigued even though it is repeatedly stimulated. The heartbeat is controlled by the AUTONOMIC NERVOUS SYSTEM.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Thorburn, "MAP kinase- and Rhodependent signals interact to regulate gene expression but not actin morphology in cardiac muscle cells," EMBO Journal, vol.
Xanthine oxidase inhibitors may improve myocardial work efficiency by sensitising cardiac muscle cells to calcium ions, which are a key determinant of cardiac muscle function.
The team's true breakthrough, however, is that the newly created cardiac muscle cells clumped together into a single unit that visibly pumps under the microscope.
Fewer than one percent of the injected cells survive and remain in the heart, and even fewer become cardiac muscle cells.
They took the cargo and the shell of the stem cell and packaged it into a biodegradable particle that, when tested in vitro, promoted the growth of cardiac muscle cells.
Schneider group's key research activities in Imperial's National Heart and Lung Institute will include discovery of enzyme pathways activated by cardiac stress that result in the apoptosis of cardiac muscle cells. According to the contract, Domainex will also conduct lead identification and optimisation studies on the serine/threonine protein kinase enzyme target mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4).
The team reported that they have taken an important step toward this goal by determining that the mechanical forces generated by the rhythmic expansion and contraction of cardiac muscle cells play an active role in the initial stage of heart valve formation.
Japanese researchers said Friday they have discovered stem cells in the heart that proliferate into cardiac muscle cells, a finding that may contribute to future medical treatment to regenerate damaged hearts.
Heart failure has been linked to abnormal calcium handling by cardiac muscle cells due to impaired activity of the SERCA2a pump.
The scientists hope to show for the first time the presence of special stem cells in human vascular walls that have the ability to develop into beating cardiac muscle cells under culture conditions.
Three other active agents, along with isoproterenol, induced the cardiac muscle cells to form tissue sheets of beating heart muscle cells.
They then induced the pluripotent cells to differentiate into cardiac muscle cells or cardiomyocytes, documenting patterns of gene expression that reflected developmental milestones and generating cells in sufficient quantity for possible clinical application.