Cardiac Arrhythmia Suppression Trial


Also found in: Acronyms.

Cardiac Arrhythmia Suppression Trial

See CAST, CAST-2.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
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Mitchell et al., "Mortality and morbidity in patients receiving encainide, flecainide, or placebo--the Cardiac Arrhythmia Suppression Trial," The New England Journal of Medicine, vol.
[9] The Cardiac Arrhythmia Suppression Trial (CAST) Investigators, "Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction," The New England Journal of Medicine, vol.
Researchers in the Cardiac Arrhythmia Suppression Trial (CAST II) had recruited 1,346 men and women who had survived a heart attack but developed mild rhythm irregularities due to damaged ventricles, the lower heart chambers.
The Cardiac Arrhythmia Suppression Trial. N Engl J Med 1991; 324:781 788.
Begun in June 1987 and designed to run until 1992, the Cardiac Arrhythmia Suppression Trial sought to compare each of the three drugs to placebo in a total of 4,400 patients who had a heart attack and developed arrhythmias within two years before enrollment in the study.
The Cardiac Arrhythmia Suppression Trial (CAST) and clarithromycin are mentioned in appropriate chapters, for example.
A recent example is the Cardiac Arrhythmia Suppression Trial (CAST) study results, which revealed an increased mortality associated with suppression of ventricular arrhythmias in survivors of myocardial infarction.(13) As Bemben et al point out, thyroid replacement in the elderly has its own risks for cardiovascular and sleletal health.(7)

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