INGREDIENTS WT% Phase A Deionized water (Aqua) 74.00 Disodium EDTA 0.05 Carbopol
980 (Lubrizol) (Carbomer) 0.15 Tealan 99 (Rita) (Triethanolamine) 0.30 Jeechem BUGL (Jeen) (Butylene glycol) 5.00 Optiphen (Brenntag Specialities) 1.00 (Phenoxyethanol, caprylyl glycol) Phase B Kostol NatureMuls (Koster Keunen) 4.50 (Candelilla/jojoba/rice bran polyglyceryl-3 esters, glyceryl stearate, cetearyl alcohol, sodium stearoyl lactylate) Peg-8 Beeswax (Koster Keunen) (Peg-8 Beeswax) 4.00 Kester Wax K-24 (Koster Keunen) (Lauryl laurate) 6.00 Belsil DM50 (Brenntag) (Dimethicone) 5.00 PROCEDURE: Combine Phase A ingredients one at a time, mixing well after each addition, while heating batch to 80-85[degrees]C.
While the blank gel only consists of the carbopol
Preparacao e caracterizacao de hidrogeis a base de Pluronic F-127 e Carbopol
934P contendo as ftalocianinas de zinco e aluminio-cloro para aplicacao topica em Terapia Fotodinamica.
Gentamicin sulphate (BP grade) was obtained as a gift from Drugfield Pharmaceuticals Limited (Ogun State, Nigeria), Carbopol
Ultrez 21[R] was obtained as a gift from Metchem Limited (Mumbai India/Lubrizol Corporation, USA), Carbopol
940[R] (Lubrizol Corporation, USA), propylene glycol, triethanolamine (TEA) (Merck Germany), Transcutol[R] was obtained as a gift from Gattefosse (Cedex, France), O-Phthalaldehyde OPA from Fluka (Steiheim Germany).
The facility specializes in the production of Carbopol
polymers and Pemulen polymeric emulsifiers.
Materials and Methods: Thermogravimetric analysis and rotational viscometry, which affect the process of the formation of carbopol
, were taken.
After obtaining the crude plant methanolic extract (leaves), it was incorporated into two types of carriers, which was based on Carbopol
Gel and lanolin/vaseline (1:1).
The hydrogels used in the release study were prepared from the following polymers: methylcellulose (MC, Sigma-Aldrich, Poznan, Poland), Carbopol
980 NF (pA1, Lubrizol, Wickliffe, USA) and polyacrylate crosspolymer 11 (PC-11, Aristoflex Velvet, Clariant, Muttenz, Switzerland).
Examples of adjuvants used with variety of vaccines include Montanide incomplete Seppic adjuvant (ISA) series, ISA 70 VG (ISA 70) and ISA 71 VG (ISA 71), and Quil A, cholesterol, dimethyl dioctadecyl ammonium bromide, and Carbopol
(QCDC) adjuvant complex, whereby the former is a water-in-oil emulsion and the latter is composed of Quil A, cholesterol, dimethyl dioctadecyl ammonium bromide (DDA), and Carbopol
(Aucouturier et al., 2006; Cox et al., 2003; Dominowski et al., 2009).
940 NF polymer, disodium ethylenediaminetetraacetic acid (EDTA), and aminomethyl propanol (AMP) were obtained from Pharma Nostra (Campinas, Brazil).
This gel is a 36% hydrogen peroxide agent with carboxypolymethylene polymer (carbopol
), having a pH=7.82.