carbonic anhydrase

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Related to Carbonic anhydrase i: Carbonic anhydrase inhibitors, Carbonic Anhydrase 9

anhydrase

 [an-hi´drās]
an enzyme that catalyzes the removal of water from a compound.
carbonic anhydrase an enzyme that catalyzes the decomposition of carbonic acid into carbon dioxide and water, facilitating transfer of carbon dioxide from tissues to blood and from blood to alveolar air.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

car·bon·ic an·hy·drase

a zinc-containing enzyme that catalyzes the interconversion of CO2 with HCO3- and H+. There are at least seven human isozymes that appear predominantly in red blood cells, secretory tissues, and muscle. A deficiency of carbonic anhydrase II can result in osteopetrosis and metabolic acidosis. The inhibition of carbonic anhydrase IV and possibly carbonic anhydrase II by sulfonamides is a current therapy in the treatment of glaucoma.
Farlex Partner Medical Dictionary © Farlex 2012

carbonic anhydrase

an enzyme that accelerates the reaction between carbon dioxide and water to form carbonic acid in the red blood cells.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Supuran, "Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII," Bioorganic Chemistry, vol.
Serum antibodies to carbonic anhydrase I and II in patients with idiopathic chronic pancreatitis and Sjogren's syndrome.
[2] Human genes: KRT20, keratin 20; CA1, carbonic anhydrase I; MS4A12, membrane-spanning 4-domains, subfamily A, member 12; CD177, CD177 molecule; SLC26AA3, solute carrier family 26, member 3.
Cui, "Proton transfer in carbonic anhydrase is controlled by electrostatics rather than the orientation of the acceptor," Biochemistry, vol.
Antibodies to mammalian carbonic anhydrase I and II failed to recognize stingray carbonic anhydrase, which has significant structural and kinetic differences from forms found in higher vertebrates (Maynard and Coleman, 1971; Maren, 1980b).
However, the enzyme Carbonic Anhydrase is used to provide an additional reaction pathway with a lower energy requirement for the conversion of this dissolved bicarbonate back to dissolved carbon dioxide.

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