He began to investigate these steps more formally about six years ago, eventually unravelling the details of carbocation
The amount of chemical bond formation was the highest for the chloro-hydrocarbon groups that are capable of stabilizing carbocations.
Its biosynthesis involves the reaction of 3-methyl-2-buten-1-ol pyrophosphate (7) to generate a transient allylic cation intermediate (8), which rapidly reacts with the electron-rich 3-methyl-3-buene-1-ol pyrophosphate (9) to form a carbon-carbon chemical bond and a second carbocation intermediate (10).
may indicate a greater usefulness for the carbocations
McClelland's research has run the gambit from physical organic chemistry, where his group pioneered the direct study of reactive intermediates of the tetrahedral intermediate and carbocation
class, to biological and medicinal organic chemistry, where his group examined the properties of several important classes of drugs.
This research group (with Alan Hopkinson) is also actively investigating destabilized carbocations
His most recent efforts have been directed towards solid-state NMR and x-ray crystallographic studies of isolable carbocations
, the thermal and photochemistry of iminium salts related to the visual pigments, and the use of photochemical methods for the fabrication of charge-mosaic piezodialysis membranes.
eq 18 probably via the formation of incipient carbocations
, Carbanions, Free Radicals, Carbenes, and Nitrenes.
12 Cyclobutyl, cyclobutyl-substituted and related carbocations
But the silicon cation proved more difficult to make than the carbocation