carbamoyl phosphate

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car·ba·mo·yl phos·phate

(kar'bă-mō-il fos'fāt),
A reactive intermediate capable of transferring its carbamoyl group to an acceptor molecule, forming citrulline from ornithine in the urea cycle and ureidosuccinate from aspartate in pyrimidine ring formation.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
[D.sub.3]-N-carbamyl-aspartate was prepared by incubating a reaction mixture (2 mL) containing 13 mmol/L 2,3,3-[D.sub.3]-aspartate, 15 mmol/L carbamyl phosphate, and 50 mmol/L triethanolamine HCl (pH 7.0) with aspartate transcarbamylase (1 kU/L) at 37[degrees]C for 2 h.
The accumulation of carbamyl phosphate, which is associated with inherited defects of the urea cycle, stimulates the pyrimidine de novo pathway, leading to increased production of orotate.