carbacephem


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carbacephem

 [kahr″bah-sef´em]
any of a class of antibiotics closely related to the cephalosporins in structure, antimicrobial activity, and use, but chemically more stable.

carbacephem

(kăr-bă-sĕph′ĕm)
A class of broad-spectrum antibiotic drugs, derived from cephalosporins, that resist degradation by bacterial beta-lactamases. One drug in this class is loracarbef.
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Also reviewed are potential new antimicrobial agents currently undergoing investigation, such as the novel oxazolidinone RWJ-416457, the new glycopeptide dalbavancin, the glycylcycline compound tigecycline, the new carbacephem BP-102 and novel rifamycin derivatives.
Activity Active Pairwise index Activity class molecules similarity 07707 Adenosine (A1) agonists 207 0.229 07708 Adenosine (A2) agonists 156 0.305 31420 Renin inhibitors 1130 0.290 42710 CCK agonists 111 0.361 64100 Monocyclic lactams 1346 0.336 64200 Cephalosporins 113 0.322 64220 Carbacephems 1051 0.269 64500 Carbapenems 126 0.260 64350 Tribactams 388 0.305 75755 Vitamin D analogues 455 0.386 TABLE 3: MDDR activity classes for DS3 data set.
coli from the Factory Creek watershed were assayed for antibiotic resistance using the disc diffusion method with the following classes of antimicrobial agents: aminoglycosides, carbacephems, cephalosporins (1st, 2nd, and 3rd generation), macrolides, penicillins, polypeptides, quinolones, sulfonamides, and tetracyclines.