Caplan lesion | definition of Caplan lesion by Medical dictionary
Caplan syndrome A condition defined by the combination of rheumatoid arthritis and pneumoconiosis linked to mining dusts—e.g., asbestos, coal, silicates.
Swollen joints, rheumatoid nodules, cough and dyspnoea.
Caplan lesion Caplan syndrome, rheumatoid pneumoconiosis Pulmonary medicine A large > 4 cm in diameter silicotic nodule, with smooth borders, peripheral palisading of macrophages, concentric internal lamination, and central necrosis; CLs may represent juxtaposition of silicotic and rheumatoid nodules. See Rheumatoid arthritis, Silicosis.