Caplan lesion

Caplan syndrome

A condition defined by the combination of rheumatoid arthritis and pneumoconiosis linked to mining dusts—e.g., asbestos, coal, silicates.

Clinical findings
Swollen joints, rheumatoid nodules, cough and dyspnoea.

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Caplan lesion

Caplan syndrome, rheumatoid pneumoconiosis Pulmonary medicine A large > 4 cm in diameter silicotic nodule, with smooth borders, peripheral palisading of macrophages, concentric internal lamination, and central necrosis; CLs may represent juxtaposition of silicotic and rheumatoid nodules. See Rheumatoid arthritis, Silicosis.

McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.