Canesten


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Related to Canesten: Canesten Oral

clotrimazole (topical)

(kloe-trye-ma-zole) ,

Canesten

(trade name),

Clotrimaderm

(trade name),

Cruex

(trade name),

Lotrimin AF

(trade name)

Classification

Therapeutic: antifungals
Pregnancy Category: B

Indications

Treatment of a variety of cutaneous fungal infections, including cutaneous candidiasis, tinea pedis (athlete’s foot), tinea cruris (jock itch), tinea corporis (ringworm), and tinea versicolor.

Action

Affects the permeability of the fungal cell wall, allowing leakage of cellular contents.

Therapeutic effects

Decrease in symptoms of fungal infection.

Pharmacokinetics

Absorption: Absorption through intact skin is minimal.
Distribution: Distribution after topical administration is primarily local.
Metabolism and Excretion: Systemic metabolism and excretion is negligible with local application.
Half-life: Not applicable.

Time/action profile

ROUTEONSETPEAKDURATION
Topunknownunknownunknown

Contraindications/Precautions

Contraindicated in: Hypersensitivity to active ingredients, additives, preservatives, or bases.
Use Cautiously in: Nail and scalp infections (may require additional systemic therapy); Obstetric / Lactation: Safety not established.

Adverse Reactions/Side Effects

Local

  • burning
  • itching
  • local hypersensitivity reactions
  • redness
  • stinging

Interactions

Drug-Drug interaction

Not known.

Route/Dosage

Topical (Adults and Children >3 yr) Apply cream or solution twice daily for 1–4 wk.

Availability (generic available)

Cream: 1%OTC
Solution: 1%OTC
In combination with: betamethasone (Lotrisone). See combination drugs.

Nursing implications

Nursing assessment

  • Inspect involved areas of skin and mucous membranes before and frequently during therapy. Increased skin irritation may indicate need to discontinue medication.

Potential Nursing Diagnoses

Risk for impaired skin integrity (Indications)
Risk for infection (Indications)

Implementation

  • Consult health care professional for proper cleansing technique before applying medication.
  • Topical: Apply small amount to cover affected area completely. Avoid the use of occlusive wrappings or dressings unless directed by health care professional.

Patient/Family Teaching

  • Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Emphasize the importance of avoiding the eyes.
  • Caution patient that some products may stain fabric, skin, or hair. Check label information. Fabrics stained from cream can usually be cleaned by handwashing with soap and warm water.
  • Patients with athlete’s foot should be taught to wear well-fitting, ventilated shoes, to wash affected areas thoroughly, and to change shoes and socks at least once a day.
  • Advise patient to report increased skin irritation or lack of response to therapy to health care professional.
  • Inform patient that early relief of symptoms may be seen in 2–3 days. For Candida, tinea cruris, and tinea corporis, 2 wk are needed, and for tinea pedis, therapeutic response may take 3–4 wk. Recurrent fungal infections may be a sign of systemic illness.

Evaluation/Desired Outcomes

  • Decrease in skin irritation and.
  • Resolution of infection.

clotrimazole (vaginal)

(kloe-trye-ma-zole) ,

Canesten

(trade name),

Clotrimaderm

(trade name),

Gyne-Lotrimin-3

(trade name),

Mycelex-7

(trade name)

Classification

Therapeutic: antifungals
Pregnancy Category: B

Indications

Treatment of vulvovaginal candidiasis.

Action

Affects the permeability of the fungal cell wall, allowing leakage of cellular contents. Not active against bacteria.

Therapeutic effects

Inhibited growth and death of susceptible Candida, with decrease in accompanying symptoms of vulvovaginitis (vaginal burning, itching, discharge).

Pharmacokinetics

Absorption: Minimal through intact skin.
Distribution: Unknown. Action is primarily local.
Metabolism and Excretion: Negligible with local application.
Half-life: Not applicable.

Time/action profile

ROUTEONSETPEAKDURATION
creamUnknown8–24 hrUnknown
tabletUnknown1–2 daysUnknown

Contraindications/Precautions

Contraindicated in: Hypersensitivity to active ingredients, additives, or preservatives; Lactation: Safety not established.
Use Cautiously in: Patients with recurrent vulvovaginal yeast infections.

Adverse Reactions/Side Effects

Genitourinary

  • itching
  • soreness
  • vulvovaginal burning

Interactions

Drug-Drug interaction

Not known.

Route/Dosage

Vaginal (Adults and Children > 12 yr) Vaginal tablets—100 mg at bedtime for 7 nights (preferred regimen for pregnancy) or 200 mg at bedtime for 3 nights. Vaginal cream—1 applicatorful (5 g) of 1% cream at bedtime for 7 days or 1 applicatorful (5 g) of 2% cream at bedtime for 3 days.

Availability (generic available)

Vaginal tablets: 100 mgOTC, 200 mgOTC
Vaginal cream: 1%OTC, 2%OTC, 10%OTC

Nursing implications

Nursing assessment

  • Inspect involved areas of skin and mucous membranes before and frequently during therapy. Increased skin irritation may indicate need to discontinue medication.

Potential Nursing Diagnoses

Risk for infection (Indications)
Risk for impaired skin integrity (Indications)

Implementation

  • Consult physician or other health care professional for proper cleansing technique before applying medication.
  • Vaginal: Applicators are supplied for vaginal administration.

Patient/Family Teaching

  • Instruct patient to apply medication as directed for full course of therapy, even if feeling better. Therapy should be continued during menstrual period.
    • Advise patient to avoid using tampons while using this product.
    • Instruct patient on proper use of vaginal applicator. Medication should be inserted high into the vagina at bedtime. Instruct patient to remain recumbent for at least 30 min after insertion. Advise use of sanitary napkins to prevent staining of clothing or bedding.
    • Advise patient to consult health care professional regarding intercourse during therapy. Vaginal medication may cause minor skin irritation in sexual partner. Advise patient to refrain from sexual contact during therapy. Advise patient that this medication may weaken latex or rubber contraceptive products. Another method of contraception should be used during treatment.
    • Advise patient to report to health care professional increased skin irritation or lack of response to therapy. A second course may be necessary if symptoms persist.
    • Advise patient to dispose of applicator after each use.
  • Advise patient that therapeutic response is usually seen after 1 wk. Before a second course of therapy is initiated, diagnosis should be reconfirmed with smears or cultures to rule out other pathogens associated with vulvovaginitis. Recurrent vaginal infections may be a sign of systemic illness.

Evaluation/Desired Outcomes

  • Decrease in skin irritation and vaginal discomfort.
  • Resolution of infection.

Canesten®

Clotrimazole Infectious disease A topical used for Candida spp and/or trichomonas infection. See Candida albicans.

Canesten

A brand name for CLOTRIMAZOLE.
References in periodicals archive ?
For more information on Canesten, visit their site at canesten.co.uk.
equally effective but a commercial product such as Canesten is
The major players operating in this market include Sanofi (Lactacyd), Bayer Group (Canesten), Nutraceutical (Emerita), Combe Incorporated.
Treatment is usually by topical anti fungal creams like Clotrimazole (Canesten) or Terbinafine (Lamasil), which work well on skin, many of these can be bought over the counter.
Fortunately, over-the-counter anti-fungal remedies such as Canesten or Daktarin are available from your pharmacist - simply apply a small amount with the tip of your finger a few times a day for fortnight.
The Consumer Care Division of Bayer HealthCare has launched Canesten Sensicare, the latest addition to Canesten's worldwide product portfolio in this region.
Furthermore, OTC manufacturers have also begun to extend into feminine hygiene wipes and Canesten Care and Vagisil both have wipes in their ranges targeted at daily use.
QI HAVE had an itchy rash under my arms for several weeks and it has not responded to Canesten cream prescribed by my GP.
Major Product: Ciproxin, Incidal Glucobay and Adalat Tablets, Canesten, Baycuten Ointment Creams and Incidal liquid.