Dendritic cells play a key role in activating an immune response--whether against a foreign microbe or a damaged body cell--so many of the most promising new cancer vaccines
use dendritic cells to train the immune system to recognize tumor cells.
The experts reckoned that cancer vaccines
and targeted therapies could help patients with lung cancer after surgery.
Oncology drugs company Champions Oncology (OtherOTC:CSBR) disclosed on Monday that it has submitted two patent applications to the US Patent and Trademark Office (USPTO) with respect to the development and use of mice with humanized immune systems to test immune-oncology drugs and therapeutic cancer vaccines
with its Champions TumorGraft platform.
When asked what he believes are the most difficult challenges he believes cancer vaccines
face today, he said, "One of the major challenges is the efficient priming of CD8 as well as CD4 T cells.
(JT) to support Corixa's development of therapeutic lung cancer vaccines
. The milestone was achieved following JT's selection of a Corixa antigen for further development.
So far, most research into cancer vaccines
has looked at proteins specific to individual tumours.
Germany-based Siemens has collaborated with Germany-based BioNTech to produce personalised cancer vaccines
There have so far only been three cancer vaccines
approved by the FDA, and many others are now nearing the end of their clinical trials.
By simply ratcheting up a tumor's temperature a few degrees--similar to the tiny temperature difference between the testes and the rest of a man's body--scientists are boosting the power of radiation, chemotherapy, and cancer vaccines
. Armed with a better understanding of how heat amplifies those treatments' effects and with new tools to heat tumors, researchers may someday give every cancer patient the bright prognosis of Foster, Armstrong, and other testicular cancer survivors.
M2 PHARMA-October 19, 2017-Lilly, CureVac Partner to Develop mRNA Cancer Vaccines