Canarypox Virus

An avipoxvirus and etiologic agent of canarypox, a disease of wild and captive birds, which can enter but not survive and multiply in human cells; it was proposed as a live vector for HIV vaccines, as it can carry a large quantity of foreign genes
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A vaccine of recombinant canarypox virus expressing feline interleukin-2 (IL-2) is approved for use in Europe as adjunctive immunotherapy after surgery for some feline cancers, including feline injection-site sarcomas, or fibrosarcomas.
Emerging Effective Cancer Option: Immunotherapy helps the body use its own weapons
However, 4 samples (18%) had antibody to canarypox virus antigen with test sample and negative control ratios (P/N values) ranging from 2.4 to 6.5 (median 4.3).
J Wildl Dis.: Relatively high prevalence of pox-like lesions in Henslow's sparrow (Ammodrammus henslowii) among nine species of migratory grassland passerines in Wisconsin, USA
Live canarypox virus that expresses the rabies virus glycoprotein has been licensed in the USA as a parenteral monovalent vaccine for cats and as a combination rabies vaccines for cats with feline panleukopenia virus, feline parvovirus, feline calicivirus vaccines included in the product (51).
Development in immunoprophylaxis against rabies for animals and humans
Both strains were found in all 3 passerine taxa, and sequences from both strains were less than 5% different from each other and from canarypox virus. In contrast, chickens in Galapagos were infected with a virus that appears to be identical in sequence to the characterized fowlpox virus and about 30% different from the canarypox/Galapagos group viruses in the regions sequenced.
J Wildl Dis: Characterization of canarypox-like viruses infecting endemic birds in the Galapagos Islands
Two vaccines are available for vaccinating equines: an inactivated WNV vaccine and a recombinant vaccine that uses canarypox virus to express WNV antigens (44,45).
Virology, pathology, and clinical manifestations of West Nile Virus disease
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