Calcium-channel blocker


Also found in: Dictionary, Thesaurus, Encyclopedia.

Calcium-channel blocker

A drug that blocks the entry of calcium into the muscle cells of small blood vessels (arterioles) and keeps them from narrowing.
References in periodicals archive ?
According to the results, current use of calcium-channel blockers for 10 or more years was associated with higher risks of ductal breast cancer and lobular breast cancer.
Treatment of poisoning caused by beta-adrenergic and calcium-channel blockers. Am J Health-Syst Pharm 2006; 63(19): 1828-1835.
They found that all three were associated with an increase in blood sugar, but more people in the thiazide group (11.6%) were diagnosed with diabetes than those assigned to take the calcium-channel blocker (9.8%) or the ACE inhibitor (8.1%).
Although many angina sufferers get relief from drugs such as beta blockers, calcium-channel blockers and nitrates, others do not.
One group was treated with a commonly used blood pressure lowering medication called a calcium-channel blocker (nifedipine).
CANADA -- Older patients who were given a prescription for a calcium-channel blocker (such as amlodipine) with clarithromycin were found to have double the risk of acute kidney injury as those given a drug of the same class with azithromycin.
Clinical equivalence in generics and brand-names was seen in all trials of beta-blockers, anti-platelet agents, angiotensin-converting enzyme (ACE) inhibitors, alpha-blockers, class 1 anti-arrhythmic agents and warfarin (Coumadin), in 10 of 11 trials of diuretics and five of seven calcium-channel blocker studies.
The first study tested the diuretic chlorthalidone against the ACE inhibitor lisinopril and amlodipine, a calcium-channel blocker.
"If we can develop a calcium-channel blocker based on this toxin, we could have a new way to identify how these channels work and develop drugs for treating pain and disease," says Zhang.
Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a goal in hypertensive treatment (INSIGHT).
This study was conducted among Ontarians 66 years and older who were treated with a calcium-channel blocker (drugs often used to treat high blood pressure) between 1994 and 2009.
11 Journal of the American Medical Association have intensified the debate over calcium-channel blockers. The latter study finds a calcium-channel blocker called isradipine may cause cardiovascular problems.

Full browser ?