Calcium-channel blocker


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Calcium-channel blocker

A drug that blocks the entry of calcium into the muscle cells of small blood vessels (arterioles) and keeps them from narrowing.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
According to the results, current use of calcium-channel blockers for 10 or more years was associated with higher risks of ductal breast cancer and lobular breast cancer.
Treatment of poisoning caused by beta-adrenergic and calcium-channel blockers. Am J Health-Syst Pharm 2006; 63(19): 1828-1835.
They found that all three were associated with an increase in blood sugar, but more people in the thiazide group (11.6%) were diagnosed with diabetes than those assigned to take the calcium-channel blocker (9.8%) or the ACE inhibitor (8.1%).
Although many angina sufferers get relief from drugs such as beta blockers, calcium-channel blockers and nitrates, others do not.
One group was treated with a commonly used blood pressure lowering medication called a calcium-channel blocker (nifedipine).
CANADA -- Older patients who were given a prescription for a calcium-channel blocker (such as amlodipine) with clarithromycin were found to have double the risk of acute kidney injury as those given a drug of the same class with azithromycin.
Clinical equivalence in generics and brand-names was seen in all trials of beta-blockers, anti-platelet agents, angiotensin-converting enzyme (ACE) inhibitors, alpha-blockers, class 1 anti-arrhythmic agents and warfarin (Coumadin), in 10 of 11 trials of diuretics and five of seven calcium-channel blocker studies.
The first study tested the diuretic chlorthalidone against the ACE inhibitor lisinopril and amlodipine, a calcium-channel blocker.
"If we can develop a calcium-channel blocker based on this toxin, we could have a new way to identify how these channels work and develop drugs for treating pain and disease," says Zhang.
Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a goal in hypertensive treatment (INSIGHT).
This study was conducted among Ontarians 66 years and older who were treated with a calcium-channel blocker (drugs often used to treat high blood pressure) between 1994 and 2009.
11 Journal of the American Medical Association have intensified the debate over calcium-channel blockers. The latter study finds a calcium-channel blocker called isradipine may cause cardiovascular problems.

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