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Finally, the location hypothesis states that the specific site of calcium entry on a micro or even nano scale determines the direction of plasticity by controlling which calcium-binding proteins
are in proximity to the calcium influx.
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in infiltrate macrophages of rheumatoid arthritis," Nature, vol.
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Calcium absorption and the vitamin [D.sub.3]-dependent calcium-binding protein
convallaria calcium-binding protein
Myeloid-related protein (MRP) 8 and MRP14, calcium-binding proteins
of the S100 family, are secreted by activated monocytes via novel, tubulin-dependent pathway.
Vitamin D acts to maintain bone integrity by promoting synthesis of calcium-binding proteins
(calbindins) required for the active transport of calcium across the intestinal wall; low vitamin D status is associated with increased risk of osteoporosis.
A large family of calcium-binding proteins
serve as sensors and buffers of the calcium ion.