calcitriol


Also found in: Dictionary, Encyclopedia, Wikipedia.

calcitriol

 [kal´sĭ-tri´ol]
1,25-dihydroxycholecalciferol; a form of vitamin D used as a calcium regulator in the management of hypocalcemia in conditions such as rickets, osteodystrophy, hypoparathyroidism, and complications of renal dialysis; administered orally or intravenously.

cal·ci·tri·ol

(kal'si-trī'ol),
1α,25-Dihydroxycholecalciferol (thus, a 1,3,25-triol); formation of calcitriol is the second step in the biologic conversion of vitamin D3 to its active form; it is more potent than calcidiol.

calcitriol

/cal·ci·tri·ol/ (kal″sĭ-tri´ol)
2. a preparation of this compound, used in the treatment of hypocalcemia, hypophosphatemia, rickets, and osteodystrophy associated with a variety of disorders.

calcitriol

[kalsit′rē·ôl]
the active form of vitamin D, a regulator of calcium metabolism.
indication It is prescribed in the management of hypocalcemia in patients undergoing chronic renal dialysis and in patients with hypoparathyroidism.
contraindications Hypercalcemia, evidence of vitamin D toxicity, malabsorption syndrome, decreased renal function, or known sensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse reactions are renal toxicity and those associated with hypercalcemia, such as soft tissue calcification.

calcitriol

A form of vitamin D3 which promotes intestinal absorption of Ca2+, increases renal tubular reabsorption of Ca2+ and reduces Ca2+ resorption by bone.
 
Indications
Postmenopausal and corticosteroid-induced osteoporosis, hypocalcaemia, hypoparathyroidism, osteomalacia, rickets, renal osteodystrophy, chronic renal dialysis.

Adverse effects
Nausea, vomiting, constipation, anorexia, headache, thirst, sweating, polyuria—all due to hypercalcaemia.

calcitriol

A vitamin D analogue drug used in the treatment of low calcium levels resulting from kidney disease. Brand names are Calcijex, Rocatrol and Silkis.

calcitriol

vitamin D derivative used to treat vitamin D deficiency, postmenopausal osteoporosis and rickets

calcitriol (kal´sitri´ol),

n brand name: Calcijex;
drug class: vitamin D3 hormone;
action: increases intestinal absorption of calcium and phosphorus;
uses: hypocalcemia in chronic renal dialysis and rickets, nutritional supplement.

calcitriol

a nonproprietary name for 1,25-dihydroxycholecalciferol; used as a calcium regulator in the management of hypocalcemia.
References in periodicals archive ?
If true, then candidate genes for autism should include all those that code for the various proteins involved in the metabolism, catabolism, transport, or binding of calcitriol.
Przybyl, Akorn's President and Chief Executive Officer stated, "We are pleased to announce the ANDA approval for Calcitriol Injection.
We expect Calcitriol alone to generate significant additional sales and profit once launched commercially.
To examine concentration-dependent effects, three concentrations (10, 100, and 1000 nM) of calcitriol were added to both NP and HP media.
Antiproliferative effects of calcitriol in B cells such as proliferation, initiation of apoptosis, decreased immunoglobulin production and inhibition of differentiation, were earlier considered to be exclusively indirectly mediated by T helper (Th) cells.
tuberculosis infection to decrease calcitriol synthesis and directly lower blood calcium levels.
5 meg twice daily or 1 meg/d for 36 weeks to 2 years or calcitriol (1,25-dihydroxyvitamin [D.
M2 EQUITYBITES-September 23, 2016-Rockwell Medical plans commercial launch of Calcitriol in the US dialysis market
M2 PHARMA-September 23, 2016-Rockwell Medical plans commercial launch of Calcitriol in the US dialysis market
Calcitriol (l,25[OH]2D) is the active hormonal form of vitamin D.
The main factors producing these abnormalities include calcitriol deficiency, phosphate retention, decreased numbers of calcium sensory receptors in the parathyroid gland, and skeletal resistance to the calcemic action of parathyroid hormone (PTH) (1).
Hallazgos histologicos semejantes se han detectado en pacientes refractarios a calcitriol en pulsos IV, sometidos a paratiroidectomia en el ano 1994 (11).

Full browser ?