S100A8

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S100A8

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which contain 2 EF-hand calcium-binding motifs and as a group regulate cell cycle progression and differentiation, as well as other cellular processes.

Molecular pathology
Altered expression of S100A8 is associated with cystic fibrosis.
References in periodicals archive ?
Antibodies to Helicobacter pylori and CagA protein are associated with the response to antibacterial therapy in patients with H.
6 In Asian countries, rate of cagA positivity has been reported in almost all strains of H.
pylori cagA-positive strains initiate delivery of CagA into the cytoplasm of the host cells via the TFSS.
pylori specific genes (16S rRNA and cagA, vacA and ureAB).
Confirmation of extracted outer membrane proteins (OMPs) and recombinant protein CagA by SDS-PAGE and western blotting Finally, to check that the recombinant protein CagA was in the supernatant (periplasmic space) or pellet (inclusion bodies) and for confirmation of extracted outer membrane proteins SDS-PAGE was performed.
pylori se une a la celula gastrica por medio del sistema de secrecion Tipo IV (SST4), el cual transloca la proteina CagA hacia el interior de la celula epitelial, y trae como consecuencia un aumento de la inflamacion, la proliferacion celular y la metaplasia de la mucosa gastrica [13,86].
The pattern of CagA and VacA proteins in Helicobacter pylori seropositive asymptomatic children in western Saudi Arabia.
After entering the epithelial cells, CagA is phosphorylated in motifs containing the amino acid sequence EPIYA, which triggers a series of events that leads to morphological epithelial alterations (12).
pylori, con cebadores que amplifican dos genes especificos, glmM de 294 pb (21) y ureA de 491 pb (22), y un gen de virulencia, cagA de 128 pb (23).
Using the now-validated recombinant CagA assay, we assessed CagA associations with such cancers.
The cagA gene can be classified into type A, B, C and D based on its 3'- terminal repetitive sequences (8), however, the association of these subtypes with clinical disease remains unclear.
Our experiments show that a cytotoxin-associated gene known as cagA is essential to induce inflammation.