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excessive growth of bony tissue. adj., adj hyperostot´ic.
frontal internal hyperostosis (hyperostosis fronta´lis inter´na) a new formation of bone tissue protruding in patches on the internal surface of the cranial bones in the frontal region, most commonly affecting women near menopause.
generalized cortical hyperostosis a hereditary disorder beginning during puberty, marked by osteosclerosis of the skull, mandible, clavicles, ribs, and diaphyses of long bones, associated with elevated blood alkaline phosphatase.
infantile cortical hyperostosis a syndrome seen in infants under six months of age, marked by fever, arthralgias, and swelling and cortical thickening of facial, trunk, and long bones. Called also Caffey's disease.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
Caffey diseaseAn autosomal dominant condition MIM 114000 characterised by fever, inflammation, swelling of affected bones (tibia, mandible, ulna and facial bones) and restlessness.
Caffey disease is linked to a mutation of COL1A1.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
U.S. pediatric radiologist, 1895–1966. He was a pioneer in pediatric radiology.
Caffey's diseaseInfantile cortical hyperostosis.
Medical Dictionary, © 2009 Farlex and Partners