cafe au lait spot

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spot

 [spot]
a circumscribed area or place, usually distinguished by its color; see also macula and tache.
actual focal spot the section of a focal spot on which there is intersection of an electron beam with an anode of an x-ray tube.
Bitot's s's foamy gray triangular spots of keratinized epithelium on the conjunctivae, a sign of vitamin A deficiency.
blind spot
café au lait spot a light brown pigmented macule seen in neurofibromatosis and albright's syndrome.
cherry-red spot the choroid appearing as a red circular area surrounded by gray-white retina, as viewed throught the fovea centralis in tay-sachs disease. Called also Tay's spot.
cotton-wool spot white or gray soft-edged opacities in the retina composed of cytoid bodies; seen in hypertensive retinopathy, lupus erythematosus, and numerous other conditions.
effective focal spot the size of a projected focal spot in a specified direction measured with a quality assurance test tool such as the slit camera.
focal spot
1. the object of a patient's gaze during distraction techniques.
2. a small area of an x-ray target that receives the main electron stream.
Forschheimer s's a fleeting skin eruption consisting of discrete rose spots on the soft palate sometimes seen in rubella just prior to the onset of the skin rash.
Koplik's s's small, irregular, bright red spots on the buccal and lingual mucosa, with a minute bluish white speck in the center of each; they are pathognomonic of beginning measles.
liver spot
1. a lay term for senile lentigo.
2. (in pl.) tinea versicolor.
mental blind spot mental scotoma.
mongolian spot a type of congenital brown to gray-blue nevus; see also mongolian spot.
Roth's s's round or oval white spots consisting of coagulated fibrin seen in the retina in a number of diseases in which a vascular insult resulting in hemorrhage is followed by healing.
Tay's spot cherry-red spot.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

café au lait spot

(kă-fā′ ō lā′)
pl.n.
A uniformly light to dark brown, sharply defined, usually oval-shaped patch of skin. The presence of six or more such spots in a child is associated with a form of neurofibromatosis.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

café au lait spot

A generic term for large smooth (“coast of California”), sharply-demarcated cutaneous macules that are light brown in white people and dark-brown in black people, due to increased epidermal melanocytes and melanin. While up to 10% of the general population has these spots, > 6 spots of > 1.5 cm is virtually diagnostic of von Recklinghausen’s disease.
 
DiffDx
Albright’s disease (see Coast of Maine appearance), Russell-Silver syndrome, congenital syphilis, Jaffe-Campanacci disease.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
RAG 11 / M growth retardation 8 -- cafe-au-lait spots radial ray defects (thumbs) pallor bruising and epistaxis hepatomegaly (5cm) splenomegaly (8cm) cafe-au-lait spots growth retardation microcephaly 2.
Although her brother and uncle had multiple cafe-au-lait spots, her mother had hundreds of skin nodules covering her face, trunk, arms, and legs.
In addition, this laser is now commonly used to treat many brown pigmented lesions, such as actinic lentigines, freckles, cafe-au-lait spots and nevus of Ota.
6 or more cafe-au-lait spots of >15mm diameter in post pubertal persons (or <5mm in prepuberty).
McCune-Albright syndrome occurs when fibrous dysplasia is accompanied by the appearance of scattered areas of melanotic skin pigmentation (cafe-au-lait spots) and sexual precocity.
Cafe-au-lait spots are generally the first feature to appear and may be accompanied (in from one to two thirds of affected people) by axillary freckling that develops in middle childhood.[13,14] Peripheral neurofibromas begin to appear at the onset of puberty.
Neurofibromatosis type I (NF-1 is characterized by multiple cafe-au-lait spots and the occurrence of neurofibromas along peripheral nerves.
The prevalence of congenital melanocytic nevi in Asians and the Mongolian spots in non-European newborns highlights this positive association with geographical area of origin.6 Congenital melanocytic nevi are also more common in darker races living in the west.7 Cafe-au-lait spots are seen more frequently in blacks and if numerous they may be an early sign of diseases like neurofibromatosis.8
* 5-6 or more cafe-au-lait spots (defined oval-shaped light brown patches greater than 0.5cm in diameter).
Cutaneous manifestations (commonly seen in NF type 1) consists of multiple cafe-au-lait spots and advanced disease with tumor (neurofibroma) arising from the nerve sheath.