cafe au lait spot

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a circumscribed area or place, usually distinguished by its color; see also macula and tache.
actual focal spot the section of a focal spot on which there is intersection of an electron beam with an anode of an x-ray tube.
Bitot's s's foamy gray triangular spots of keratinized epithelium on the conjunctivae, a sign of vitamin A deficiency.
blind spot
café au lait spot a light brown pigmented macule seen in neurofibromatosis and albright's syndrome.
cherry-red spot the choroid appearing as a red circular area surrounded by gray-white retina, as viewed throught the fovea centralis in tay-sachs disease. Called also Tay's spot.
cotton-wool spot white or gray soft-edged opacities in the retina composed of cytoid bodies; seen in hypertensive retinopathy, lupus erythematosus, and numerous other conditions.
effective focal spot the size of a projected focal spot in a specified direction measured with a quality assurance test tool such as the slit camera.
focal spot
1. the object of a patient's gaze during distraction techniques.
2. a small area of an x-ray target that receives the main electron stream.
Forschheimer s's a fleeting skin eruption consisting of discrete rose spots on the soft palate sometimes seen in rubella just prior to the onset of the skin rash.
Koplik's s's small, irregular, bright red spots on the buccal and lingual mucosa, with a minute bluish white speck in the center of each; they are pathognomonic of beginning measles.
liver spot
1. a lay term for senile lentigo.
2. (in pl.) tinea versicolor.
mental blind spot mental scotoma.
mongolian spot a type of congenital brown to gray-blue nevus; see also mongolian spot.
Roth's s's round or oval white spots consisting of coagulated fibrin seen in the retina in a number of diseases in which a vascular insult resulting in hemorrhage is followed by healing.
Tay's spot cherry-red spot.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

café au lait spot

(kă-fā′ ō lā′)
A uniformly light to dark brown, sharply defined, usually oval-shaped patch of skin. The presence of six or more such spots in a child is associated with a form of neurofibromatosis.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

café au lait spot

A generic term for large smooth (“coast of California”), sharply-demarcated cutaneous macules that are light brown in white people and dark-brown in black people, due to increased epidermal melanocytes and melanin. While up to 10% of the general population has these spots, > 6 spots of > 1.5 cm is virtually diagnostic of von Recklinghausen’s disease.
Albright’s disease (see Coast of Maine appearance), Russell-Silver syndrome, congenital syphilis, Jaffe-Campanacci disease.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Six or more cafe-au-lait macules of over 5 mm in greatest diameter in prepubertal individuals and over 15 mm in greatest diameter in postpubertal individuals.
Cafe-au-lait macules (CALMs) are sharply defined, light-brown patches that vary in size from 0.5 to 50 cm.
Cafe-au-lait spots, pigmented, light brown macules located on nerves, with smooth edges (coast of California) (12) http://en.
but in our case, there is association of cafe-au-lait macules.
Segmental neurofibromatosis is a rare disorder characterized by cafe-au-lait macules and/or neurofibromas following a regional distribution with its prevalence estimated at about 0.0027%.3 Riccardi established the clinical features of SNF and classified this different presentation first as NF type 5.5 It has been suggested that SNF is related to postzygotic mutation of the NF type 1 gene, leading to somatic mosaicism.
The diagnosis is essentially based on cafe-au-lait macules, freckling and/or neurofibromas situated dermatomally.7,8 The prevalence of the disease-associated systemic involvement and complications in SNF is much lower than in the generalized disease.2,3 There have been reports of SNF associated with visceral neurofibromas, soft tissue hypertrophy, skeletal abnormality, unilateral renal agenesis and renal angiomyolipomas.3 SNF has been linked to other malignancies rarely such as peripheral nevre sheath tumour, malignant melanoma, bronchoalveolar lung carcinoma, colon cancer, and Hodgkin\'s lymphoma.8 Kajimoto et al.
MPNST was followed in order by plexiform neurofibroma, optic glioma, skin tumors, learning disabilities, and cafe-au-lait macules (Table 1).
Physical Examination: Dermatological status - On skin examination there were multiple flat, hypo pigmented macule present ranging from a few millimeters to several centimeters in diameter, some of them pedunculated; multiple cafe-au-lait spots with diameter > 1, 5 cm (fig 1); axillary and inguinal freckling.
Conclusion: Mongolian blue spot are the commonest pigmented birthmarks observed followed by cafe-au-lait macules and congenital melanocytic nevi.
The patient started developing the generalized Cafe-au-lait spots, starting to arise first from the abdomen by the age of about 5years, followed by small generalized, neurofibromatotic lesions.
Cutaneous manifestations (commonly seen in NF type 1) consists of multiple cafe-au-lait spots and advanced disease with tumor (neurofibroma) arising from the nerve sheath.