CYP


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CYP

Abbreviation for cytochrome P450 enzymes; usually followed by an arabic numeral, a letter, and another arabic numeral (for example, CYP 2D6). These enzymes are found in and on the smooth endoplasmic reticulum of liver and other cells and are responsible for a large number of drug biotransformation reactions.

CYP

Abbreviation for cytochrome P-450 enzymes; usually followed by an arabic numeral, a letter, and another arabic numeral (e.g., CYP 2D6). These enzymes are found in and on the smooth endoplasmic reticulum of liver and other cells and are responsible for a large number of drug biotransformation reactions.

couple-year of protection

,

CYP

In family planning, the number of days per year that any method of birth control will prevent conception. Abstinence from sexual intercourse, or sterilization of both members of a couple, provides absolute (365 days/year) protection. Other methods of family planning or fertility inhibition are relatively less effective. Couples that attempt penile withdrawal before male climax (coitus interruptus) have the lowest levels of CYP of any method. Condoms provide a moderate increase in contraceptive effectiveness but are less effective than intrauterine devices, contraceptive pills, or contraceptive implants.

cytochrome

(si'to-krom) [? + chroma, color]
An iron-containing protein found in the mitochondria of eukaryotic cells; each is given a letter name (a, b, c). The cytochrome transport system (electron transport chain) is the last stage in aerobic cell respiration. See: cytochrome oxidase; cytochrome P450; cytochrome transport system

cytochrome P450

Abbreviation: CYP
A group of enzymes present in every type of cell in the body except red blood cells and skeletal muscle cells. They are important in metabolizing substances normally present in the body such as steroids, fat-soluble vitamins, fatty acids, prostaglandins, and alkaloids. The P450 enzymes also detoxify drugs and a great number of environmental pollutants, such as carcinogens present in tobacco smoke and charcoal-broiled meat, polychlorinated biphenyls, and dioxin. Specialized types of cytochrome P450 are involved in the synthesis of nitric oxide.

cytochrome P450

Abbreviation: CYP
A group of enzymes present in every type of cell in the body except red blood cells and skeletal muscle cells. They are important in metabolizing substances normally present in the body such as steroids, fat-soluble vitamins, fatty acids, prostaglandins, and alkaloids. The P450 enzymes also detoxify drugs and a great number of environmental pollutants, such as carcinogens present in tobacco smoke and charcoal-broiled meat, polychlorinated biphenyls, and dioxin. Specialized types of cytochrome P450 are involved in the synthesis of nitric oxide.
See also: cytochrome
References in periodicals archive ?
To investigate the inhibitory effects of MA on the activities of nine CYP isoforms, we performed CYP inhibition assays using a cocktail of probe substrates and an LC-MS/MS system.
Lack of training was cited by focus group members as a barrier to integrating child mental health promotion in the work of a CYP nurse.
CYP3A4 genotypes were determined by amplification of a 186-bp CYP 3A4-G or a 187-bp -A DNA fragment.
Total cost and CYP are positively and strongly correlated, indicating that if total cost increases, then CYP tends to increase.
In this study, the effects of MA on the above-mentioned CYPs activities were also investigated in rat liver microsomes, employing phenacetin (CYP1A2), tolbutamide (CYP2C11), dextromethorphan (CYP2D6), chlorzoxazone (CYP2E1) and testosterone (CYP3A2) as the probe substrates.
Recent research indicates that patients with chronic renal dysfunction or failure have reduced or variable activity of CYP enzymes such as CYP2C9 and CYP3A4 as well as the transporter permeability glycoprotein (P-gp).
Coventry teenager Kaseem Mahmood suffered heartbreak in the final of the CYP championship in Stoke.
The CYP stands for Club for Young People because the term Boys Club would eliminate all possibility of having girl members.
The authors write, "This comparison should enable researchers to better utilize the mouse as a model system for the study of these CYP genes in humans and in other mammals.
Denison's work focused on the Ah receptor's ability to trigger any of several genes, such as CYP 1A1, that make enzymes to begin detoxifying poisons.
In the context of Pakistan, the relationship between birth averted and CYP is as:
Osmetech expects further commercial progress in 2009 by expanding the eSensor XT-8 test menu to include an extended Warfarin Sensitivity Test panel that includes CYP 4F2, a CYP 2C9 Genotyping panel, a venous thrombosis panel of Factor V, Factor II and MTHFR and a Respiratory Virus Pathogen panel.