CLIP2

(redirected from CYLN2)

CLIP2

A gene on chromosome 7q11.23 that encodes a member of the cytoplasmic linker protein family, which are thought to mediate the interaction between specific membranous organelles and microtubules. CLIP2 associates with microtubules and an organelle (the dendritic lamellar body).

Molecular pathology
CLIP2 is hemizygously deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23.
References in periodicals archive ?
Con todos los hallazgos se hizo impresion diagnostica de SWB y se realizo FISH para la region del SWB, la cual evidencio delecion de los genes ELN, LIMK1 y CYLN2 (7q11) en uno solo de los cromosomas 7 (Figura 2).