CXCR7

CXCR7

A gene on chromosome 2q37.3 that encodes a member of the G protein-coupled receptor family which is a receptor for CXCL12/SDF1 and a coreceptor with CXCR4 for some HIV isolates.
References in periodicals archive ?
CXCR7 expression in nasopharyngeal carcinoma tissues correlates with disease severity.
We will focus on unravelling how CXCR4 and CXCR7 are or can be modulated (small molecules, pepducins, nanodies) and investigate the effects on oncogenic responses.
A novel mechanism by which SDF protects cardiac cells from palmitate-induced endoplasmic reticulum stress and apoptosis via CXCR7 and AMPK/p38 MAPK-mediated interleukin-6 generation," Diabetes, vol.
Work by another lab called Klein's attention to CXCR7, a receptor that binds to CXCL12.
The CXCL12 ligand works through 7-transmembrane receptors CXCR4 and CXCR7 to affect changes in a variety of neural cells and alter migration.
CXCR7 is a novel chemokine receptor whose function was discovered and characterized by ChemoCentryx.
25-fold (Supplementary Table S4, Figure 4), while 46 cytokine receptors (CSF3R, CXCR7, IL-17RA, IL-18R1, IL-1R1, IL-1R2, IL-20RA, IL-21R, IL-2RG, IL-4I1, IL-5RA, IL-7R, IL-9R, LILRB3, TGFBR1, TLR1, TLR15, TLR21, TLR5, TLR6, TLR7, TNFRSF13B, TNFRSF13C, TNFRSF1B, TRAT1, XCR1, etc.
CXCL12, CXCR4 and CXCR7 expression in brain metastases.