CXCR2(redirected from CXCR-2)
CXCR2A gene on chromosome 2q35 that encodes a seven-transmembrane G protein-coupled receptor belonging to the CXC chemokine receptor family, which selectively binds IL8, as well as CXCL1, CXCL3, GRO/MGSA and NAP-2. CXCR2 is a potent neutrophil chemotactic factor and mediates neutrophil migration to sites of inflammation; it mediates IL8’s angiogenic effects on intestinal microvascular endothelial cells.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.