CXCL5


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CXCL5

A gene on chromosome 4q13.3 that encodes an inflammatory chemokine, which is involved in neutrophil activation and co-produced with IL-8 in response to stimulation by either IL-1 or tumour necrosis factor-alpha (TNF-alpha).
References in periodicals archive ?
Jeyaseelan, "CXCL1 regulates pulmonary host defense to Klebsiella infection via CXCL2, CXCL5, NF-[kappa]B, and MAPKs," Journal of Immunology, vol.
showed that the cAMP agonists PGE [sub]2 and forskolin cause a marked increase in the production of several pro-inflammatory chemokines, such as CXCL5, CXCL7, and CCL2 in the GM-CSF-induced macrophages, and that this effect was potentiated by PDE4 inhibition.
Nuestro analisis de expresion global con microarreglos revelo diferencias significativas en la expresion de quimiocinas CXCL- y CCL- tales como CXCL1 (Gro-[alfa]), CXCL2 (Gro-[beta]), CXCL5 (ENA-78), CXCL8 (IL-8) y CXCL10 (IP-10).
Andrew Loudon from The University of Manchester said that they have found key molecule known as CXCL5 that facilitates lung inflammation which is a key regulator of how immune cells get into tissues.
Professor Loudon said: "We found a key molecule known as CXCL5 that facilitates lung inflammation which is a key regulator of how immune cells get into tissues.
The molecule, called CXCL5, controls sensitivity to pain from ultraviolet (UV) radiation.
Increased serum CXCL1 and CXCL5 are linked to obesity, hyperglycemia, and impaired islet function.
Here we analyzed the expression of TCDD-inducible cytokines including CXCL chemokines CXCL1, CXCL2, CXCL3, CXCL5, CXCL7, CXCL10, and CXCL14.
Now, a new study has shown that obese people have large amounts of the molecule CXCL5, produced by certain cells in fatty tissue.
SERPINE1, ICAM1, F3, MMP3, CCL2, CXCL5, CXCL9, and VCAM1; and CD69, PLAU, PLAT, SELP, SELE, HLA-DRA, IL1 A, PLAUR, SAA1, TIMP2, CCL26, TGFB1, NR4A2, CSF1, and CXCL10: tissue remodeling during inflammation and angiogenesis
The researchers behind the study say that an inflammatory protein, known as CXCL5, rises and falls with obesity and subsequent weight loss in humans.