The predictive model was calculated as the sum of the predictor values weighted by regression coefficients and included the addition of cetuximab to chemotherapy ([beta]=+1.771), mutations in 6 genes: ATP6V1B1 ([beta]=-0.165) CUL9
([beta]=-0.726), ERBB2 ([beta]=-1.140), LY6G6D ([beta]=-0.994), PTCH1 ([beta]=+0.821), and RBMXL3 ([beta]=-0.477), and constant value (a=-0.255).
For instance, mutations of the KDM6A, CUL9
, FDG6, AKAp3, and RFN139 genes are associated with the development of PVT in advanced HBV-related HCC .
The trend in ionization potential for the copper complexes is CuL8 < CuL9
< CuL7 < CuL4 < CuL6.
DRAMATIC Parsy72 presents the Tyne gorge at its best STUNNING CWhatPhoto captures Northumberland Street COLOURFUL Reader Ross Teasdale photographs the Blyth beach huts in winter SILENT NIGHT Cul9
on a quiet, frosty, night on the Tyne bridge EXPLOSIVE Reader K Arran's picture called 'Wipeout' taken during a "little walk at the weekend"