Also found in: Acronyms, Wikipedia.


Abbreviation for cyclophosphamide.
Farlex Partner Medical Dictionary © Farlex 2012


A gene on chromosome 2q33-qter that encodes a member of the cytochrome P450 superfamily of enzymes, which catalyse reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP27A1 is a mitochondrial protein that oxidises cholesterol intermediates as part of the bile-synthesis pathway. It catalyses the first step in the oxidation of the side chain of sterol intermediates and has a vitamin D3-25-hydroxylase activity. Because the conversion of cholesterol to bile acids is the major route for eliminating cholesterol from the body, CYP27A1 is important for cholesterol homeostasis.

Molecular pathology
CYP27A1 mutations cause cerebrotendinous xanthomatosis.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
This order follows a previous USD 70m order from the TSA announced in June 2018 for CTX 9800 Explosives Detection Systems (EDS) to be deployed at ten airports across the US.
These CTX 9800 systems utilise computed tomography (CT) imaging and will used in US airports as security equipment upgrades.
The work of our group [30] also showed that CTX has the ability to downmodulate the IgG1 and IgG2a antibody production induced by the immunization of mice with human serum albumin (HSA) emulsified in complete Freund's adjuvant (CFA) or adsorbed in Aluminium hydroxide (Alum), even when administered 1 hour before or 3 days after antigen immunization.
fumigatus was cultured from lung tissue of both IPA and CTX + IPA mice treated with rapamycin or IL-12 or without treatment [Figure 1]a,[Figure 1]b,[Figure 1]c, while control mice were negative.
As part of the agreement payments are shared between CRT, the Wellcome Trust, CTX and CTx's Australian research partners including Bionomics.
Both formulations utilise the CTX peptide-based skin-penetration platform technology.
Hoar Construction's partnership with RMHC CTX embodies the company's core values: family-orientation, stewardship, the relentless pursuit of improvement, and abidance of the golden rule - treating others as you wish to be treated.
In comparison, the range of mononuclear cell infiltration in the lungs of mice in the CTX group (Figure 2(c)) and FZFA+CTX group (Figure 2(d)) was smaller, and the alveolar structure was relatively complete.
One of the most exciting updates is the option to switch on a CTX mosaic, allowing users to view and zoom in on these high-definition images.
The delivery order is for the company's CTX 9800 DSi and CTX 9400 DSi explosive detection systems (EDS) which are valued in excess of USD17m.
In this study we intended to find out, which type of scales provides a better sensitivity for the responsiveness of oncological patients undergoing chemotherapy (CTX) and concomitant mistletoe therapy (MT).