CTNS


Also found in: Acronyms.

CTNS

A gene on chromosome 17p13 that encodes a 7-transmembrane domain protein, which transports cystine out of lysosomes driven by the H+ electrochemical gradient of the lysosomal membrane.

Molecular pathology
CTNS mutations cause nephropathic cystinosis, a lysosomal storage disease.
References in periodicals archive ?
cTns are clearly known to increase in blood postinfarction; release and loss of Tns in chronic diseased hearts support serum evidence of increased cTnI and cTnT in acute myocardial ischemia, unstable angina, or non-Q-wave MI patients pointing toward poor prognosis [38, 39].
(4) Harland Bartholomew, "The San Francisco Bay Region: A Statement Concerning the Nature and Importance of a Plan for Future Growth," TS submitted to the Regional Plan Association, September 1925, 7, 20 (RPA Records, Ctn. 1).
The sequence number for the subject and treatment assignment was allocated through an interactive electronic response system hosted by the Nutrition and Health Technology Centre (CTNS).
How many clusters in the solution, how nodes is partitioned, number of nodes within each cluster, and how the corresponding CTNs must be selected in a way that helps to achieve the goal of minimizing the resources needed to carry the traffic demands.
Coyne invited CTNS to cosponsor the series of research conferences with the Vatican Observatory.
This study similarly conducted an experiment by applying a carboxyl group to the CNT surface by using nitrogen to improve the dispersibility of CTNs. Our results showed that dispersibility increased through the carboxyl group (Figure 1) and, with the CNT surface exhibiting a negative charge, the specimen was connected to the anode for coating.
Jenson, "You Wonder Where The Body Went," CTNS Bulletin I 1.1 (Winter 1991) 20-24; H.
It was decided that the 12 "CTNs" (confectioner, tobacconist and newsagents) were no longer in keeping with Finlays' trading format.
Although cystinosis can manifest either in infancy or adolescence, mutations in the same gene, CTNS, which encodes cystinosin, appear to be involved in all forms of the disease.
The troponins are released from the damaged myocardial cells so that cardiac troponins (cTns) appear in the blood as early as 3-4 hours of an acute episode and remain elevated for 4-14 days.
These are excellent prognostic indicator in patients with (UA) and is very useful parameter for stratifying risk in Acute Coronary Syndrome (ACS) patient and their predictive value is superior to that of CK-MB alone, 5- The early serial measurement of cTns is a more accurate predictor of early coronary artery reperfusion after thrombolytic therapy as compared to CK-MB and myoglobin and it is also identified a sub to group of patients with unstable coronary syndrome in whom prolonged antithrombotic treatment with low-molecular weight heparin can improve the prognosis, figure.