Interestingly, [HIF1[alpha] and VEGF mRNA expression from OSA patients indicates a positive correlation with the hypoxia clinical parameter, nighttime oxygen saturation levels < 90% (CT90).
The reported parameters included sleep efficiency, wake after sleep onset (WASO), sleep latency, REM latency, rapid-eye movement (REM) sleep, nonREM (NREM) sleep (stages 1-3), snoring sounds, apnea-hypopnea index (AHI), arousal index, spontaneous arousals, respiratory effort-related arousals (RERA), leg movement arousals, periodic leg movements in sleep (PLMS), PLMS in REM and NREM, oxygen saturation (Sp[O.sub.2]), and CT90.