KDM5B

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KDM5B

A gene on chromosome 1q32.1 that encodes lysine-specific demethylase 5B, which interacts with FOXG1 and PAX9 as a transcriptional co-repressor. Lysine K-specific methylase may act as a tumour suppressor for melanoma.

Molecular pathology
KDM5B favours breast cancer cell proliferation by repressing tumour suppressor genes BRCA1 and HOXA5.

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The range of dust-lead loading 4 to 89,921 [micro]g/[ft.sup.2] in CT-25 compared to 2 to 21,068 [micro]g/[ft.sup.2] in CT31. The Mann-Whitney U Test revealed positive relations between soil-lead and dustlead.

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