NKX2-5

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NKX2-5

A gene on chromosome 5q34 that encodes a homeobox transcription factor implicated in commitment to, and/or differentiation of, the myocardial lineage. It acts as a transcriptional activator of ANF in co-operation with GATA4.

Molecular pathology
NKX2-5 mutations cause atrial septal defect with atrioventricular conduction defect, tetralogy of Fallot, and congenital hypothyroidism non-goitrous type 5.
References in periodicals archive ?
Murray said they have met with CSX several times explaining the impact their service has on MEC's operations.
CSX, based in Jacksonville, Florida, is a premier transportation company, providing rail, intermodal and rail-to-truck transload services and solutions to customers across a broad array of markets, including energy, industrial, construction, agricultural, and consumer products.
We re proud to partner with CSX to create more welcoming school environments for the students we serve, said Ted Marquis, Vice President of Care Force, City Year.
Monday night, a CSX official listened to neighbors' complaints about whistles, idling engines, screeches and slams associated with railcars being coupled, and other nighttime noises from the tracks and rail yard.
The improvement projects are designed to increase the vertical clearances at 61 locations on CSX rail lines in the region to accommodate intermodal trains carrying double-stacked intermodal containers.
CSX funded the remaining $400,000 as part of its commitment to reducing emissions and using less fuel.
In the CSX case, the taxpayer had argued that the payments were SUB payments because the employees receiving them had already been laid off and these payments had simply changed the employees' involuntary separation status from indefinite to permanent.
The transfer of ownership of the High Line from CSX to the City marks another important milestone in our efforts to create a one-of-a-kind public space for all New Yorkers," said Mayor Bloomberg.
A down application means trains stop running, which translates directly into lost money," said a spokesperson of CSX Technology, Inc.
Caucedo will have the first modern container handling in the Dominican Republic and will sustain large container traffic," says Curtis Foltz, vice president of Latin America for CSX.
We had to adapt our Web booking system to some of the unique requirements of the military, such as the fact we needed to include a military traffic control number," said Paul Vicinanzo, Director, Government Sales & Marketing, of CSX Lines, Elizabeth, N.
This town 75 miles southwest of Cleveland will be the biggest beneficiary of the $10 billion deal by CSX Corp.