GZMB

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GZMB

A gene on chromosome 14q11.2 that encodes an enzyme necessary for target cell lysis in cell-mediated immune responses, and which is linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis. GZMB cleaves caspase-3, -7, -9 and -10, activating enzymes that mediate apoptosis.
References in periodicals archive ?
It has been shown that courts of law are increasingly intervening to grant medical parole to prisoners where the Department of Correctional Services and the CSPBs have been reluctant to do so in a manner that is irrational, unreasonable and against the rights of prisoners.
With this video conferencing capacity, built with funding from the Criminal Asset Recovery Account (CARA), victims can be informed to go to their nearest CSPB offices and be linked to the actual parole board hearings .