Also found in: Acronyms.
CRYAAA gene on chromosome 21q22.3 that encodes alpha crystallin A, a protein induced by heat shock that belongs to the small heat shock protein (sHSP or HSP20) family. Alpha crystallins have features of molecular chaperones, but do not renature and release proteins like true chaperones.
Defects of CRYAA cause autosomal dominant cataracts (OMIM:604219).
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