In fact, 60% of CRSwNP patients, 58% of severe CRSsNP patients, and 33% of moderate CRSsNP patients said they made more than five physician visits in the past year for nose and sinus symptoms.
In addition, a large proportion of respondents expressed frustration with the inadequate symptom relief produced by their current intranasal corticosteroid (87% of CRSwNP patients, 86% of severe CRSsNP patients, and 63% of moderate CRSsNP patients).
They evaluated the effect of gender on the prevalence of CRSwNP, aspirin sensitivity, and asthma status, and used enzyme-linked immunosorbent assay to compare levels of eosinophil cationic protein and anti-dsDNA antibodies in NP extracts from men and women.
Although women comprised 50% of controls and CRS patients without NP, a significantly smaller proportion of CRSwNP patients were female (35%).
We thought we would find that CRSwNP was more prevalent and severe in women, especially because these patients have asthma and some features of local autoimmunity, which can be more prevalent and severe in women," Dr.