DPYSL5

(redirected from CRMP5)
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DPYSL5

A gene on chromosome 2p23.3 that encodes a member of the collapsin response mediator protein family, which form homotetramers and heterotetramers with other proteins. DPYSL5 is thought to play a role in neuronal differentiation and/or axon growth.
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(i) Subacute onset (days or up to 12 wk) of seizures, short-term memory loss, confusion, and psychiatric symptoms (ii) Neuropathologic or radiologic evidence (MRI, SPECT, PET) of involvement of the limbic system (iii) Exclusion of other possible etiologies of limbic dysfunction (iv) Demonstration of a cancer within 5 yr of the diagnosis of neurologic symptoms or the development of classic symptoms of limbic dysfunction in association with a well-characterized paraneoplastic antibody (Hu, Ma2, CRMP5, amphiphysin, Ri) TABLE 3: Differential diagnoses of limbic encephalitis.