CPDA-1


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citrate

 [sit´rāt, si´trāt]
any anionic form, salt, or ester of citric acid.
citrate phosphate dextrose (CPD) a solution containing citric acid, sodium citrate, monobasic sodium phosphate, and dextrose that is the primary anticoagulant used for preservation of whole blood or red blood cells for up to 21 days. The official USP name is anticoagulant citrate phosphate dextrose solution.
citrate phosphate dextrose adenine (CPDA-1) an anticoagulant solution, containing citric acid, sodium citrate, monobasic sodium phosphate, dextrose, and adenine, used for the preservation of whole blood and red blood cells for up to 35 days; it extends red cell survival by providing adenine needed for the maintenance of red cell ATP levels. The official USP name is anticoagulant citrate phosphate dextrose adenine solution.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

CPDA-1

Citrate phosphate dextrose-adenine 1. A medium which supplies ATP, and extends the shelf life of packed red cells destined for transfusion to 35 days with a higher ATP level than earlier-generation red cell preservation media.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Em relacao aos CH, empregam-se os sistemas usuais para a preservacao de eritrocitos, incluindo as bolsas com CPDA-1 como anticoagulante e solucoes aditivas, como ADSOL ou SAGM, para preservacao dos eritrocitos entre 4 [+ or -] 2 [degrees]C.
[11,12,13,14] Therefore, adenine is added to the anticoagulant CPDA-1, prolonging the duration of storage.
Sousa et al., "Evaluation of hematologic, Blood gas, and select biochemical variables in ovine whole blood stored in CPDA-1 bags," Veterinary Clinical Pathology, vol.
One milliliter of CPDA-1 (Jorgenson Laboratories, Loveland, CO, USA) was drawn into a 12-mL syringe with a 20-gauge needle.
Biochemical parameters: Twenty five units each of whole blood, CPDA-1 RBC, SAGM RBC were tested serially for the following biochemical parameters: supernatant potassium ([K.sup.+]), pH, lactate, haemoglobin, glucose and red cell 2,3 DPG up to 21 days of storage.
Two 8-mL samples of marrow bonewere withdrawn from each dog, one containing 2.0mL CPDA-1 (citrate phosphate dextrose adenine-1) anticoagulant solution and the other 2.0mL anticoagulant solution composed of 1.0mL heparin (5000 IU/mL) and 1.0mL phosphate buffered saline (PBS).
Traditionally, a request for fresh blood transfusion, (less than seven-day-old and collected in CPDA-1 [citrate phosphate dextrose adenine]), is due to the three following concerns in using older blood:
The filtered content was transferred to a blood bag (500mL blood collection bag, CPDA-1, JP Pharmaceutical Industry A.S.), from which anticoagulant had previously been removed.
Parameter biochemical and hemogasometric of the total blood stored of dogs in plastic stock markets I contend CPDA-1 and CPD/SAG-M.