NR2F1

(redirected from COUP-TFI)

NR2F1

A gene on chromosome 5q14 that encodes a transcription factor that binds to the ovalbumin promoter and, in conjunction with S300-II, stimulates initiation of transcription.
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Chicken ovalbumin upstream promoter-transcription factor I and II (Coup-tfI and Coup-tfII), are transiently expressed in the ventricular zone in a relatively early phase of the developing brain, and have been suggested to be involved in the acquisition of gliogenic competence by NSCs.
(2008) Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development.