CORO1A

CORO1A

A gene on chromosome 16p11.2 that encodes an actin-binding protein that may be a key component of the cytoskeleton of highly motile cells, and which may play a role in both the invagination of large chunks of the plasma membrane and the formation of plasma membrane protrusions during cell locomotion. It is expressed in the brain, thymus, spleen, bone marrow and lymph nodes.
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References in periodicals archive ?
For in vivo observation of macrophages and neutrophils behavior, we used 4 dpf tg (coro1a:dGFP;lyz:DsRed2) hkz04t;nz50, tg (lyz:eGFP) transgenic lines and tg (flk:GFP;lyzDsRed) hybrid lines.
To verify the specific effect of mpx on neutrophil migration, tg (coro1a:eGFP; lyzDsRed2) hkz04t; nz50 transgenic zebrafish lines were used in which macrophages and neutrophils were labeled with green and yellow fluorescent colors, respectively.
Crosier (Department of Molecular Medicine and Pathology, School of Medical Sciences, The University of Auckland, Auckland, New Zealand) for providing Tg (coro1a: eGFP; lyz Dsred) and Tg (lyz Dsred) lines.